CAS 1622262-55-8

BRCA1-IN-2

Description:

BRCA1-IN-2, identified by its CAS number 1622262-55-8, is a small molecule inhibitor specifically designed to target the BRCA1 protein, which plays a crucial role in DNA repair mechanisms. This compound is of particular interest in cancer research, especially in the context of tumors with BRCA1 mutations, as it may enhance the efficacy of certain chemotherapeutic agents by disrupting the normal function of BRCA1. The characteristics of BRCA1-IN-2 include its molecular structure, which typically features specific functional groups that facilitate its interaction with the BRCA1 protein. It is often evaluated for its potency, selectivity, and pharmacokinetic properties, which are essential for determining its potential therapeutic applications. Additionally, studies may focus on its solubility, stability, and bioavailability, which are critical factors influencing its effectiveness in clinical settings. Overall, BRCA1-IN-2 represents a promising avenue for targeted cancer therapy, particularly in personalized medicine approaches for patients with BRCA1-related malignancies.

Formula: C₂₆H₃₃N₄O₇P

Synonyms:

• BRCA1 IN 2,BRCA1IN2,BRCA-1-IN-2
• Glycinamide, N-[3-(1H-indol-3-yl)-1-oxopropyl]-O-phosphono-L-seryl-N-(4-phenylbutyl)-
• BRCA1-IN-2

BRCA1-IN-2

CAS: 1622262-55-8

BRCA1-IN-2

Purity: ≥98%

Molecular weight: 544.54g/mol

Ref: 54-BUP21940

N-(4-Phenylbutyl)-2-[[(2S)-2-[[3-(1H-indole-3-yl)propanoyl]amino]-3-(phosphonooxy)propanoyl]amino]acetamide

CAS: 1622262-55-8

N-(4-Phenylbutyl)-2-[[(2S)-2-[[3-(1H-indole-3-yl)propanoyl]amino]-3-(phosphonooxy)propanoyl]amino]acetamide is a potent and selective inhibitor of protein interactions. It is an inhibitor of the receptor tyrosine kinase, Fms-like tyrosine kinase 3 (FLT3) and has been shown to inhibit the proliferation of FLT3 expressing cells in vitro. In addition, it has been shown to activate the potassium channel Kv1.5 and inhibit voltage gated sodium channels. N-(4-Phenylbutyl)-2-[(2S)-2-[3-(1H indole-3-yl)propanoic acid amide] amide acetamide can be used as a research tool for investigating protein interactions or as an antibody for cell biology applications.

Formula: C₂₆H₃₃N₄O₇P

Purity: Min. 95%

Molecular weight: 544.5 g/mol

Ref: 3D-XPC26255

BRCA1-IN-2

CAS: 1622262-55-8

BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.

Formula: C₂₆H₃₃N₄O₇P

Purity: 98.04%

Color and Shape: Solid

Molecular weight: 544.54

Ref: TM-T10601