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CAS 162227-13-6

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Hydroxy Terbinafine

Description:
Hydroxy Terbinafine is a metabolite of the antifungal agent terbinafine, which is primarily used to treat fungal infections, particularly those affecting the skin and nails. This compound is characterized by its ability to inhibit the enzyme squalene epoxidase, which plays a crucial role in the biosynthesis of ergosterol, an essential component of fungal cell membranes. Hydroxy Terbinafine is typically a white to off-white crystalline powder, and it is soluble in organic solvents but has limited solubility in water. Its pharmacokinetic properties suggest that it has a relatively long half-life, allowing for sustained antifungal activity. The compound is often studied for its efficacy and safety profile, particularly in relation to its parent drug, terbinafine. Additionally, it may exhibit some antifungal activity on its own, although its primary significance lies in its role as a metabolite. Overall, Hydroxy Terbinafine is an important compound in the context of antifungal therapy and pharmacology.
Formula:C3H6O7P
InChI:InChI=1/C3H7O7P/c4-1(2(5)6)3(7)11(8,9)10/h1,3-4,7H,(H,5,6)(H2,8,9,10)/p-1
Synonyms:
  • (5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-yn-1-ol
  • (5E)-2,2-dimethyl-7-[m3-dihydroxy-3-phosphonopropanoate
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