CAS 162239-35-2
:ent-idoxuridine
Description:
Ent-idoxuridine, with the CAS number 162239-35-2, is an antiviral compound that is a derivative of the nucleoside analog idoxuridine. It is primarily characterized by its ability to inhibit viral replication, making it particularly relevant in the treatment of certain viral infections. The structure of ent-idoxuridine features a modified uridine backbone, which enhances its efficacy against specific viruses by interfering with their nucleic acid synthesis. This compound exhibits selectivity for viral enzymes over host cellular enzymes, which contributes to its therapeutic potential while minimizing toxicity to host cells. Additionally, ent-idoxuridine is known for its stability and solubility in various solvents, which facilitates its formulation in pharmaceutical preparations. Its pharmacological profile includes a favorable absorption and distribution in biological systems, although specific pharmacokinetic parameters may vary. Overall, ent-idoxuridine represents a significant advancement in antiviral therapy, particularly in the context of treating infections caused by DNA viruses.
- 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo-
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Found 4 products.
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo-
CAS:Formula:C9H11IN2O5Molecular weight:354.0985ent-idoxuridine
CAS:<p>Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.</p>Formula:C9H11IN2O5Purity:Min. 95%Molecular weight:354.1 g/mol
