CAS 162301-05-5

ECENOFLOXACIN

Description:

Enrofloxacin, identified by its CAS number 162301-05-5, is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine. It exhibits broad-spectrum antibacterial activity against a variety of Gram-negative and some Gram-positive bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. Enrofloxacin is characterized by its high lipophilicity, which enhances its penetration into bacterial cells. The compound is typically administered orally or via injection and is known for its rapid absorption and distribution in tissues. It is important to note that enrofloxacin is not approved for use in food-producing animals in some regions due to concerns about antibiotic resistance and potential residues in food products. Side effects may include gastrointestinal disturbances and, in rare cases, effects on cartilage development in young animals. As with all antibiotics, appropriate use is crucial to minimize the development of resistance and ensure efficacy in treating bacterial infections.

Formula: C₁₉H₂₁FN₄O₃

InChI: InChI=1/C19H21FN4O3/c1-19-5-14(21)12(19)7-23(8-19)17-13(20)4-10-15(25)11(18(26)27)6-24(9-2-3-9)16(10)22-17/h4,6,9,12,14H,2-3,5,7-8,21H2,1H3,(H,26,27)/t12-,14-,19-/m0/s1

SMILES: C[C@]12C[C@@H]([C@@H]2CN(C1)c1c(cc2c(=O)c(cn(C3CC3)c2n1)C(=O)O)F)N

Synonyms:

• Ecenofloxacin [INN]
• (+)-7-((1R,5S,6S)-6-Amino-1-methyl-3-azabicyclo(3.2.0)hept-3-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• Unii-3613Zy362L
• 1,8-Naphthyridine-3-carboxylic acid, 7-((1R,5S,6S)-6-amino-1-methyl-3-azabicyclo(3.2.0)hept-3-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, rel-( )-
• 7-[(1R,5S,6S)-6-amino-1-methyl-3-azabicyclo[3.2.0]hept-3-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• Ecenofloxacin