CAS 16234-10-9

Thieno[3,2-D]Pyrimidin-4(3H)-One

Description:

Thieno[3,2-D]Pyrimidin-4(3H)-one is a heterocyclic organic compound characterized by a fused ring system that includes both a thiophene and a pyrimidine moiety. This compound typically exhibits a planar structure due to the conjugated system, which can contribute to its electronic properties. It is known for its potential biological activity, often being investigated for its role in medicinal chemistry, particularly as a scaffold for the development of pharmaceuticals. The presence of the carbonyl group at the 4-position of the pyrimidine ring enhances its reactivity and can facilitate interactions with biological targets. Additionally, the compound may exhibit moderate solubility in organic solvents, which is common for similar heterocycles. Its unique structure allows for various substitutions, leading to derivatives with potentially enhanced pharmacological properties. Overall, Thieno[3,2-D]Pyrimidin-4(3H)-one represents a significant class of compounds in drug discovery and development, particularly in the search for novel therapeutic agents.

Formula: C₆H₄N₂OS

Synonyms:

• 3H,4H-thieno[3,2-d]pyrimidin-4-one

4-Hydroxythieno[3,2-d]pyrimidine

CAS: 16234-10-9

Formula: C₆H₄N₂OS

Purity: 97%

Color and Shape: Solid

Molecular weight: 152.1738

Ref: IN-DA001T1K

Thieno[3,2-d]pyrimidin-4(3H)-one

CAS: 16234-10-9

Thieno[3,2-d]pyrimidin-4(3H)-one

Purity: 97%

Molecular weight: 152.17g/mol

Ref: 54-OR80270

1H,4H-Thieno[3,2-d]pyrimidin-4-one

CAS: 16234-10-9

Formula: C₆H₄N₂OS

Purity: 97%

Color and Shape: Solid

Molecular weight: 152.17

Ref: 10-F017496

Thieno[3,2-d]pyrimidin-4(1H)-one

CAS: 16234-10-9

Formula: C₆H₄N₂OS

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 152.17

Ref: 3B-T3301

Thieno[3,2-d]pyrimidin-4(1H)-one

CAS: 16234-10-9

Thieno[3,2-d]pyrimidin-4(1H)-one is a synthetic compound that has been shown to inhibit cancer cell proliferation. It has an amination reaction at the 2' position of the pyrimidine ring and this pharmacophore is responsible for its anticancer activity. Thieno[3,2-d]pyrimidin-4(1H)-one inhibits leukemia HL-60 cells with a potency similar to that of imatinib. It also inhibits hepg2 cells, which are tumor cells derived from hepatocytes. The kinase selectivity profile of thieno[3,2-d]pyrimidin-4(1H)-one does not show any toxicity towards normal cells such as human skin fibroblasts or human umbilical vein endothelial cells. Thieno[3,2-d]pyrimidin-4(1H)-one exhibits a safety profile similar

Formula: C₆H₄N₂OS

Purity: Min. 95%

Molecular weight: 152.17 g/mol

Ref: 3D-RAA23410