CAS 162359-56-0

Fingolimod hydrochloride

Description:

Fingolimod hydrochloride is a synthetic compound primarily used as an immunomodulatory drug for the treatment of multiple sclerosis. It functions as a sphingosine-1-phosphate receptor modulator, which helps to retain lymphocytes in lymph nodes, thereby reducing their availability to migrate to the central nervous system and cause inflammation. The substance is typically presented as a white to off-white crystalline powder, with a molecular formula that reflects its complex structure. Fingolimod hydrochloride is soluble in water and exhibits a moderate log P value, indicating its lipophilicity. The compound is administered orally, and its pharmacokinetics involve extensive first-pass metabolism, leading to the formation of an active metabolite. Side effects may include bradycardia, elevated liver enzymes, and increased risk of infections, necessitating monitoring during treatment. Overall, Fingolimod hydrochloride represents a significant advancement in the management of relapsing forms of multiple sclerosis, offering a novel mechanism of action compared to traditional therapies.

Formula: C₁₉H₃₃NO₂·ClH

InChI: InChI=1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H

InChI key: InChIKey=SWZTYAVBMYWFGS-UHFFFAOYSA-N

SMILES: C(CC(CO)(CO)N)C1=CC=C(CCCCCCCC)C=C1.Cl

Synonyms:

• 1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, hydrochloride
• 1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, hydrochloride (1:1)
• 2-(4-octylphenylethyl)-2-aminopropane-1,3-diol HCL
• 2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol,HCl
• 2-Amino-2-[2-(4-Octylphenyl)Ethyl]-1,3-Propanediol, Hydrochloride
• 2-Amino-2-[2-(4-Octylphenyl)Ethyl]Propane-1,3-Diol
• 2-Amino-2-[2-(4-Octylphenyl)Ethyl]Propane-1,3-Diol Hydrochloride (1:1)
• 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol
• 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride
• 2-Amino-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride
• Fingolimod HCL(FTY720)
• Fingolimod HCl
• Fty 720
• Fty720
• Fty720 Hydrochloride
• Gilenya
• Imusera

Fingolimod Hydrochloride

CAS: 162359-55-9, 162359-56-0

Formula: C₁₉H₃₃NO₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 343.94

Ref: 3B-F1018

FINGOLIMOD HYDROCHLORIDE CRS

CAS: 162359-56-0

FINGOLIMOD HYDROCHLORIDE CRS

Color and Shape: Powder

Ref: 41-Y0002055

Fingolimod Hydrochloride

CAS: 162359-56-0

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₉H₃₃NO₂·HCl

Color and Shape: White Powder

Molecular weight: 343.22781

Ref: 45-1270480

1,​3-​Propanediol, 2-​amino-​2-​[2-​(4-​octylphenyl)​ethyl]​-​, hydrochloride (1:1)

CAS: 162359-56-0

Formula: C₁₉H₃₄ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 343.9318

Ref: IN-DA001T0Y

Fingolimod hydrochloride

CAS: 162359-56-0

Fingolimod hydrochloride

Purity: ≥98%

Molecular weight: 343.93g/mol

Ref: 54-BUP14837

Fingolimod hydrochloride

CAS: 162359-56-0

Formula: C₁₉H₃₄ClNO₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder or crystals

Molecular weight: 343.93

Ref: 7W-GP3498

Fingolimod HCl

CAS: 162359-56-0

Formula: C₁₉H₃₃NO₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 307.48 36.46

Ref: 4Z-F-321

Fingolimod-d4 HCl (1,3-propane-1,1,3,3-d4-diol)

CAS: 1346604-90-7, 162359-56-0

Purity: 99 atom % D

Molecular weight: 347.96

Ref: 3U-D7971

Fingolimod Hydrochloride

Controlled Product

CAS: 162359-56-0

Formula: C₁₉H₃₃NO₂·ClH

Color and Shape: Neat

Molecular weight: 343.93

Ref: 86-MM3554.00

Fingolimod hydrochloride

CAS: 162359-56-0

Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).

Formula: C₁₉H₃₄ClNO₂

Purity: 99.26% - 99.83%

Color and Shape: White Solid

Molecular weight: 343.93

Ref: TM-T2539

Fingolimod Hydrochloride

CAS: 162359-56-0

Formula: C₁₉H₃₃NO₂·ClH

Color and Shape: White To Off-White

Molecular weight: 343.93

Ref: TR-F805000

Fingolimod hydrochloride

CAS: 162359-56-0

Sphingosine-1-phosphate receptor modulator; immunomodulator

Formula: C₁₉H₃₃NO₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 343.93 g/mol

Ref: 3D-FA23612

Fingolimod HCl - Bio-X ™

CAS: 162359-56-0

Fingolimod is a sphingosine 1-phosphate receptor modulator that is used in the treatment of relapsing-remitting form of multiple sclerosis. It is also being studies to manage lung complications in patients with COVID-19. This drug binds to various sphingosine 1-phospahte receptors and suppresses the exit of lymphocytes from lymph nodes.

Formula: C₁₉H₃₃NO₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 343.93 g/mol

Ref: 3D-BF164458

Fingolimod hydrochloride

CAS: 162359-56-0

Formula: C₁₉H₃₄ClNO₂

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 343.94

Ref: 10-F048115