CAS 1624-62-0

estrone 3-methyl ether

Description:

Estrone 3-methyl ether, with the CAS number 1624-62-0, is a synthetic derivative of estrone, a naturally occurring estrogen. This compound is characterized by the presence of a methyl ether group at the 3-position of the estrone structure, which influences its biological activity and solubility. Estrone 3-methyl ether is typically a white to off-white crystalline solid, and it is soluble in organic solvents such as ethanol and chloroform, but has limited solubility in water. The compound exhibits estrogenic activity, making it relevant in studies related to hormone replacement therapy and reproductive health. Its molecular formula reflects the presence of carbon, hydrogen, and oxygen atoms, consistent with steroid structures. Estrone 3-methyl ether is often used in biochemical research and pharmaceutical applications, particularly in the context of understanding estrogenic effects and developing therapeutic agents. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₁₉H₂₄O₂

InChI: InChI=1/C19H24O2/c1-19-10-9-15-14-6-4-13(21-2)11-12(14)3-5-16(15)17(19)7-8-18(19)20/h4,6,11,15-17H,3,5,7-10H2,1-2H3

InChI key: InChIKey=BCWWDWHFBMPLFQ-VXNCWWDNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC)=CC4)(CC1)[H])[H])(CCC2=O)[H]

Synonyms:

• (+)-Estrone methyl ether
• (8R,9S,13S,14S)-3-Methoxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
• 3-Methoxyestra-1,3,5(10)-Trien-17-One
• 3-Methoxyestra-1,3,5(10)triene-17-one
• 3-Methoxyestra-1,3,5-trien-17-one
• 3-Methoxyestrone
• 3-Methoxyoestra-1,3,5(10)-Trien-17-One
• 3-Methylether-Estrone
• 3-O-Methylestrone
• Estra-1,3,5(10)-trien-17-one, 3-methoxy-
• Estrone O-methyl ether
• Mestrone
• NSC 88911
• Oestrone methyl ether
• Estrone 3-methyl ether
• 1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3-METHYL ETHER
• 3-METHOXY-1,3,5[10]-ESTRATRIEN-17-ONE
• 1,3,5(10)-ESTRATRIEN-3-OL-17-ONE METHYL ETHER
• ESTRONE 3-METHYL ETHER MM(CRM STANDARD)
• 3-Methoxy-1(10),2,4-estratriene-17-one
• EINECS 216-613-3
• Methyl-3-hydroxy-1,3,5[10] estratrien-17-one

Estrone 3-Methyl Ether

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Purity: >97.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 284.40

Ref: 3B-E0917

Estra-1,3,5(10)-trien-17-one, 3-methoxy-

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 284.3927

Ref: IN-DA001T2T

3-O-Methyl Estrone

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 284.40

Ref: 4Z-E-114

Estrone 3-Methyl Ether

CAS: 1624-62-0

Estrone 3-Methyl Ether

Purity: 98%

Molecular weight: 284.4g/mol

Ref: 54-OR1027382

Estrone 3-Methyl Ether

Controlled Product

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Color and Shape: Neat

Molecular weight: 284.39

Ref: 86-MM0282.01

Estrone 3-methyl ether

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Purity: ≥ 97.0% (dried basis)

Color and Shape: White to off-white or faint yellow powder

Molecular weight: 284.39

Ref: 7W-GK5552

3-O-Methyl Estrone

Controlled Product

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Color and Shape: White To Dark Brown

Molecular weight: 284.39

Ref: TR-M304710

3-O-Methyl Estrone-d5 (Major)

Controlled Product

CAS: 1624-62-0

Formula: C₁₉H₁₉D₅O₂

Color and Shape: Neat

Molecular weight: 289.42

Ref: TR-M304712

3-O-Methyl estrone

Controlled Product

CAS: 1624-62-0

3-O-Methyl estrone is a trifluoroacetic acid derivative of oestrone that is used in the synthesis of premarin. 3-O-Methyl estrone has chemical reactions that are similar to those of oestrone, but it also has a hydroxyl group on the C3 position. The product research and development of 3-O-methyl estrone led to discovering its structural similarity to estradiol and its potential as an estrogen receptor modulator. This compound showed high affinity for the estrogen receptor alpha (ERα) and ERβ, with binding constants of 1.9 nM and 0.87 nM, respectively. Molecular modeling studies revealed that 3-O-methyl estrone has a higher affinity for ERα than for ERβ. Kinetic data suggests that this compound could be potentially used in hormone replacement therapy or to treat osteoporosis in postmenopausal women.

Formula: C₁₉H₂₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 284.39 g/mol

Ref: 3D-FM25494

3-O-Methyl Estrone

CAS: 1624-62-0

Formula: C₁₉H₂₄O₂

Molecular weight: 284.4

Ref: ST-EA-CP-E30002

Estrone 3-methyl ether

CAS: 1624-62-0

Estrone 3-methyl ether is an active molecule that can be used in life science related research. The CAS number of Estrone 3-methyl ether is 1624-62-0.

Formula: C₁₉H₂₄O₂

Color and Shape: Solid

Molecular weight: 284.399

Ref: TM-T84876