CAS 1625-39-4

6α-Methylhydrocortisone

Description:

6α-Methylhydrocortisone, with the CAS number 1625-39-4, is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is a derivative of hydrocortisone, modified at the 6α position to enhance its biological activity. This compound is characterized by its steroidal structure, which includes four fused carbon rings typical of steroid hormones. Its chemical formula reflects the presence of multiple functional groups, including hydroxyl groups, which contribute to its solubility and reactivity. 6α-Methylhydrocortisone is often utilized in research and clinical settings for its ability to modulate immune responses and reduce inflammation. It can be administered in various forms, including topical applications and systemic treatments. The compound's pharmacological effects are mediated through its interaction with glucocorticoid receptors, influencing gene expression and cellular processes. As with other corticosteroids, its use may be associated with a range of side effects, necessitating careful consideration of dosage and duration of treatment. Overall, 6α-Methylhydrocortisone serves as an important tool in the management of various inflammatory and autoimmune conditions.

Formula: C₂₂H₃₂O₅

InChI: InChI=1S/C22H32O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h9,12,14-15,17,19,23,25,27H,4-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1

InChI key: InChIKey=FQWLSWNUHFREIQ-PJHHCJLFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]

Synonyms:

• (6Alpha,11Beta)-11,17,21-Trihydroxy-6-Methylpregn-4-Ene-3,20-Dione
• (6α,11β)-11,17,21-Trihydroxy-6-methylpregn-4-ene-3,20-dione
• 6-Alpha-Methylhydrocortisone
• 6α-Methyl-11β,17α,21-trihydroxy-4-pregnene-3,20-dione
• 6α-Methylcortisol
• 6α-Methylhydrocortisone
• Corticosterone, 17-hydroxy-6α-methyl-
• NSC 19618
• Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6α,11β)-
• Pregn-4-ene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-
• Premedrol

Methylprednisolone EP Impurity F

CAS: 1625-39-4

Formula: C₂₂H₃₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 376.49

Ref: 4Z-P-11146

6α-Methyl Hydrocortisone

CAS: 1625-39-4

Applications A metabolite of Cortisone (C696500).
References Mashkovskii, M., et al.: Med. Agents, 2, 34 (2002),

Formula: C₂₂H₃₂O₅

Color and Shape: Off-White To Beige

Molecular weight: 376.49

Ref: TR-M312515

6α-Methyl hydrocortisone

Controlled Product

CAS: 1625-39-4

Please enquire for more information about 6α-Methyl hydrocortisone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₃₂O₅

Purity: Min. 95%

Molecular weight: 376.49 g/mol

Ref: 3D-FM183403

Methylprednisolone EP Impurity F

CAS: 1625-39-4

Formula: C₂₂H₃₂O₅

Molecular weight: 376.49

Ref: ST-EA-CP-M14006