CAS 162520-00-5

Benzoic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]thio]-

Description:

Benzoic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]thio]- is a chemical compound characterized by its benzoic acid core, which features a thioether substituent derived from a long-chain dodecatriene. The presence of the thio group indicates that it contains sulfur, which can influence its reactivity and solubility. The compound's structure includes multiple double bonds, contributing to its unsaturation and potential for various chemical reactions, such as addition or oxidation. The trimethyl groups suggest a branched structure, which can affect its physical properties, such as melting and boiling points, as well as its steric hindrance. This compound may exhibit biological activity due to its complex structure, making it of interest in fields such as organic chemistry and biochemistry. Additionally, its CAS number, 162520-00-5, allows for easy identification and reference in chemical databases. Overall, this compound's unique features make it a subject of interest for further research and application in various chemical contexts.

Formula: C₂₂H₃₀O₂S

InChI: InChI=1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+

InChI key: InChIKey=WUILNKCFCLNXOK-CFBAGHHKSA-N

SMILES: S(C/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C1=C(C(O)=O)C=CC=C1

Synonyms:

• S-Farnesylthiosalicylic acid
• Benzoic acid, 2-[(3,7,11-trimethyl-2,6,10-dodecatrienyl)thio]-, (E,E)-
• Benzoic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-
• Benzoic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]thio]-
• 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid
• irasib
• 2-(((2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl)thio)benzoicacid
• Salirasib(S-Farnesylthiosalicylic aci)
• (3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL)-2-THIOBENZOIC ACID
• Salirasib (Farnesyl Thiosalicylic Acid)
• Salirasib USP/EP/BP
• FTS
• CS-1744
• Salirasib
• 2-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoic acid
• S-trans,trans-Farnesylthiosalicylic acid
• (E,E)-2-[(3,7,11-TriMethyl-2,6,10-dodecatrienyl)thio]benzoic Acid
• Unii-mzh0om550m
• Farnesylthiosalicylate

Salirasib

CAS: 162520-00-5

Formula: C₂₂H₃₀O₂S

Purity: >96.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 358.54

Ref: 3B-A3351

Benzoic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-

CAS: 162520-00-5

Formula: C₂₂H₃₀O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.5374

Ref: IN-DA001T7Z

Salirasib

CAS: 162520-00-5

Salirasib

Purity: ≥98%

Molecular weight: 358.54g/mol

Ref: 54-BUP17138

Salirasib

CAS: 162520-00-5

Salirasib

Purity: 98%

Molecular weight: 358.54g/mol

Ref: 54-OR1026378

Salirasib

CAS: 162520-00-5

Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.

Formula: C₂₂H₃₀O₂S

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 358.54

Ref: TM-T6163

trans,trans-Farnesyl thiosalicylic acid

CAS: 162520-00-5

Farnesyl thiosalicylic acid (FTSA) is a synthetic compound that exhibits potent anticancer activity. FTSA binds to the active site of the enzyme protein kinase C-alpha (PKC-α), which prevents its phosphorylation and activation. This prevents the activation of the mitogen-activated protein kinases, which are involved in cell proliferation and differentiation. FTSA also inhibits cancer cell migration by blocking MMP-9 activity, leading to tumor regression. FTSA has been shown to be effective against chemotherapy resistant breast cancer cells, as well as cancer cells from other tissues such as colon, prostate, and ovary.

Formula: C₂₂H₃₀O₂S

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 358.54 g/mol

Ref: 3D-FF23230

SALIRASIB

CAS: 162520-00-5

Formula: C₂₂H₃₀O₂S

Purity: 98%

Molecular weight: 358.54

Ref: 10-F468408

trans,trans Farnesyl Thiosalicylic Acid

Controlled Product

CAS: 162520-00-5

Applications It is a new specific nontoxic drug with a mild hydrophobic nature, which acts as a Ras antagonist and can therefore be used for stent applications as well as for local cancer treatment.
References Marciano, D., et al.: J. Med. Chem., 38, 1267 (1995), Li, Y., et al.: J. Cardiovasc. Pharmacol., 48, 184 (2006), Rao, S., et al.: Am. J. Cardiol., 97, 1478 (2006),

Formula: C₂₂H₃₀O₂S

Color and Shape: Neat

Molecular weight: 358.54

Ref: TR-F102500