CAS 162558-25-0

N(alpha)-fmoc-N(beta)-boc-L-2,3-diamino-propionic acid

Description:

N(alpha)-Fmoc-N(beta)-Boc-L-2,3-diamino-propionic acid is a protected amino acid commonly used in peptide synthesis. It features two distinct protective groups: the Fmoc (9-fluorenylmethoxycarbonyl) group at the alpha amino position and the Boc (tert-butyloxycarbonyl) group at the beta amino position. These protective groups are crucial for selective deprotection during the synthesis process, allowing for the controlled assembly of peptides. The compound is characterized by its ability to form stable peptide bonds, making it valuable in the development of peptide-based therapeutics. Its structure includes a propionic acid backbone, which contributes to its solubility and reactivity. The presence of two amino groups allows for the introduction of various side chains, enhancing its versatility in synthetic applications. Additionally, the compound is typically handled under inert conditions to prevent degradation and ensure optimal reactivity. Overall, N(alpha)-Fmoc-N(beta)-Boc-L-2,3-diamino-propionic acid is a significant building block in the field of organic and medicinal chemistry.

Formula: C₂₃H₂₆N₂O₆

InChI: InChI=1/C23H26N2O6/c1-23(2,3)31-21(28)24-12-19(20(26)27)25-22(29)30-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)/t19-/m1/s1

SMILES: CC(C)(C)OC(=NC[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Synonyms:

• Fmoc-Dap(Boc)-OH
• Fmoc-Dpr(Boc)-OH
• Fmoc-L-2,3-Diaminopropionic acid(Boc)
• Fmoc-Dap(Boc)
• 3-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]alanine
• 3-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine
• N-Fmoc-N'-Boc-L-2,3-Diaminopropionic acid
• Fmoc-L-Dap(Boc)

(S)-3-(Boc-amino)-2-(Fmoc-amino)propionic acid, 95%

CAS: 162558-25-0

As lysine residue its 3-amino group is often used for carrying a tag moiety such as a fluorescent dye, a quencher or biotin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

Formula: C₂₃H₂₆N₂O₆

Purity: 95%

Molecular weight: 426.47

Ref: 02-H51987

Fmoc-Dap(Boc)-OH

CAS: 162558-25-0

Bachem ID: 4018520.

Formula: C₂₃H₂₆N₂O₆

Purity: 99.7%

Color and Shape: White

Molecular weight: 426.47

Ref: 01-4018520

L-Alanine, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 162558-25-0

Formula: C₂₃H₂₆N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 426.4623

Ref: IN-DA001T8K

3-[(tert-Butoxycarbonyl)amino]-L-alanine, N-FMOC protected

CAS: 162558-25-0

3-[(tert-Butoxycarbonyl)amino]-L-alanine, N-FMOC protected

Purity: 98%

Color and Shape: White Powder

Molecular weight: 426.46g/mol

Ref: 54-OR14667

(S)-3-(tert-Butoxycarbonylamino)-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]propionic Acid

CAS: 162558-25-0

Formula: C₂₃H₂₆N₂O₆

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 426.47

Ref: 3B-B6107

Fmoc-Dap(Boc)-OH

CAS: 162558-25-0

Formula: C₂₃H₂₆N₂O₆

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 426.47

Ref: 7W-GM7760

N-α-Fmoc-N β-Boc-L-2,3-diaminopropionic acid

CAS: 162558-25-0

N-alpha-Fmoc-Nbeta-Boc-L-2,3-diaminopropionic acid is a supramolecular compound that has antiproliferative effects on cancer cells. It can be used to inhibit the activity of tyrosine phosphatases, which are enzymes that regulate cell proliferation and differentiation. This compound has been shown to have synergistic effects with other chemotherapeutic agents in vitro and in vivo. It has also been shown to have a high binding affinity for polyacrylamide gels and is stable under various conditions.

Formula: C₂₃H₂₆N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 426.46 g/mol

Ref: 3D-FF47790

Fmoc-Dap(Boc)-OH

CAS: 162558-25-0

M03241 - Fmoc-Dap(Boc)-OH

Formula: C₂₃H₂₆N₂O₆

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 426.469

Ref: 10-M03241