CAS 162635-03-2
:Temsirolimus Acetonide
Description:
Temsirolimus Acetonide, with the CAS number 162635-03-2, is a derivative of temsirolimus, which is an inhibitor of the mammalian target of rapamycin (mTOR). This compound is primarily utilized in the treatment of certain types of cancer, particularly renal cell carcinoma. It exhibits characteristics typical of mTOR inhibitors, including the ability to interfere with cell cycle progression and angiogenesis, thereby inhibiting tumor growth. Temsirolimus Acetonide is a white to off-white powder that is soluble in organic solvents but has limited solubility in water. Its mechanism of action involves the inhibition of the mTOR pathway, which plays a crucial role in cell growth, proliferation, and survival. The compound is often administered via injection and is known for its pharmacokinetic properties, which include a relatively long half-life, allowing for sustained therapeutic effects. As with many pharmaceuticals, it may have side effects, and its use is typically monitored in clinical settings to manage potential adverse reactions.
Formula:C59H91NO16
InChI:InChI=1/C59H91NO16/c1-35-19-15-14-16-20-36(2)47(69-11)31-43-24-22-41(7)59(68,76-43)53(64)54(65)60-26-18-17-21-44(60)55(66)74-48(32-45(61)37(3)28-40(6)51(63)52(71-13)50(62)39(5)27-35)38(4)29-42-23-25-46(49(30-42)70-12)75-56(67)58(10)33-72-57(8,9)73-34-58/h14-16,19-20,28,35,37-39,41-44,46-49,51-52,63,68H,17-18,21-27,29-34H2,1-13H3/b16-14+,19-15+,36-20+,40-28+/t35-,37-,38-,39-,41-,42+,43+,44+,46-,47+,48+,49-,51-,52+,59-/m1/s1
Synonyms:- Rapamycin 42-(2,2,5-Trimethyl-1,3-dioxane-5-carboxylate)
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Found 3 products.
Temsirolimus Acetonide
CAS:Controlled Product<p>Applications Rapamycin 42-ester derivative.<br>References Singh, K., et al.: J. Antibiot., 32, 630 (1979), Sehgal, S., et al.: Clin. Biochem., 31, 335 (1998), Abraham, R., et al.: Cell, 111, 9 (2002),<br></p>Formula:C59H91NO16Color and Shape:NeatMolecular weight:1070.35
