CAS 162666-34-4

flutimide

Description:

Flutimide is a chemical compound classified as a non-steroidal anti-inflammatory drug (NSAID) and is primarily recognized for its use in veterinary medicine, particularly in the treatment of inflammatory conditions in animals. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing inflammation and pain. Flutimide is typically administered in the form of a salt, enhancing its solubility and bioavailability. The compound exhibits moderate lipophilicity, which influences its distribution in biological systems. Its pharmacokinetic properties include a relatively short half-life, necessitating multiple doses for sustained therapeutic effects. Flutimide is also noted for its potential side effects, which may include gastrointestinal disturbances and liver toxicity, particularly with prolonged use. As with many NSAIDs, careful consideration of dosage and monitoring for adverse reactions is essential in its application. Overall, flutimide serves as an important tool in managing inflammatory conditions, particularly in veterinary contexts.

Formula: C₁₂H₁₈N₂O₃

InChI: InChI=1/C12H18N2O3/c1-7(2)5-9-11(15)14(17)12(16)10(13-9)6-8(3)4/h5,7-8,17H,6H2,1-4H3/b9-5-

SMILES: CC(C)/C=C\1/C(=O)N(C(=O)C(=N1)CC(C)C)O

Synonyms:

• 2,6-(1H,3H)-Pyrazinedione, 1-hydroxy-5-(2-methylpropyl)-3-(2-methylpropylidene)-, (3Z)-
• 2,6-(1H,3H)-Pyrazinedione, 1-hydroxy-5-(2-methylpropyl)-3-(2-methylpropylidene)-, (Z)-
• (3Z)-1-hydroxy-5-(2-methylpropyl)-3-(2-methylpropylidene)pyrazine-2,6(1H,3H)-dione
• Flutimide
• (5Z)-1-hydroxy-3-(2-methylpropyl)-5-(2-methylpropylidene)pyrazine-2,6-dione

Flutimide

Controlled Product

CAS: 162666-34-4

Formula: C₁₂H₁₈N₂O₃

Color and Shape: Neat

Molecular weight: 238.28

Ref: TR-F498700

Flutimide

CAS: 162666-34-4

Flutimide is a nonsteroidal antiandrogen, which is synthesized chemically. It functions by competitively inhibiting the binding of androgens, such as testosterone, to androgen receptors. This interferes with the action of androgens at the cellular level, leading to a reduction in the growth effects mediated by these hormones.

Formula: C₁₂H₁₈N₂O₃

Purity: Min. 95%

Molecular weight: 238.28 g/mol

Ref: 3D-MGA66634

Flutimide

CAS: 162666-34-4

Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.

Formula: C₁₂H₁₈N₂O₃

Color and Shape: Solid

Molecular weight: 238.28

Ref: TM-T70355