CAS 1627091-47-7

MLi-2

Description:

As of my last update in October 2023, specific information regarding the chemical substance "MLi-2" with the CAS number "1627091-47-7" is not widely available in standard chemical databases or literature. This may indicate that it is a relatively new compound, a specialized research chemical, or not extensively characterized in public resources. Generally, when evaluating a chemical substance, one would consider its molecular structure, physical properties (such as melting and boiling points), solubility, reactivity, and potential applications. Additionally, safety data, including toxicity and handling precautions, would be crucial for any chemical. If "MLi-2" is part of ongoing research or development, further details may emerge in scientific publications or patents. For accurate and specific information, consulting specialized databases or scientific literature directly related to this compound would be necessary.

Formula: C₂₁H₂₅N₅O₂

Synonyms:

• rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole
• MLi-2
• 1H-Indazole, 3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-, rel-

MLi-2

CAS: 1627091-47-7

MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.

Formula: C₂₁H₂₅N₅O₂

Purity: 98.96%

Color and Shape: Solid

Molecular weight: 379.46

Ref: TM-T16115

rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole

CAS: 1627091-47-7

Formula: C₂₁H₂₅N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.4555

Ref: IN-DA01E6U7

MLi-2

CAS: 1627091-47-7

MLi-2

Purity: ≥98%

Molecular weight: 379.46g/mol

Ref: 54-BUP05424

Rel-(2S,6R)-2,6-Dimethyl-4-(6-(5-(1-Methylcyclopropoxy)-1H-Indazol-3-Yl)Pyrimidin-4-Yl)Morpholine

CAS: 1627091-47-7

Rel-(2S,6R)-2,6-Dimethyl-4-(6-(5-(1-Methylcyclopropoxy)-1H-Indazol-3-Yl)Pyrimidin-4-Yl)Morpholine

Purity: 98%

Molecular weight: 379.46g/mol

Ref: 54-OR1023326

MLi-2

CAS: 1627091-47-7

A brain-penetrant inhibitor of leucin-rich repeat kinase 2 (LRRK2) with IC50 = 0.76 nM and anti-parkinsonian activity. Gain-of-function mutations in LRRK2 gene lead to increased familial and idiopathic risk of developing the disease. The inhibitors of the kinase activity have therapeutic potential against Parkinson’s disease.

Formula: C₂₁H₂₅N₅O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 379.46 g/mol

Ref: 3D-FD157083

MLI-2

CAS: 1627091-47-7

Purity: 98%

Molecular weight: 379.4639893

Ref: 10-F816661

MLi-2

Controlled Product

CAS: 1627091-47-7

Formula: C₂₁H₂₅N₅O₂

Color and Shape: Neat

Molecular weight: 379.455

Ref: TR-M425473