CAS 1627494-13-6

8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide

CAS: 1627494-13-6

Formula: C₂₄H₂₅F₂N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 457.4698

Ref: IN-DA001TE3

(R)-8-(1-((3,5-Difluorophenyl)Amino)Ethyl)-N,N-Dimethyl-2-Morpholino-4-Oxo-4H-Chromene-6-Carboxamide

CAS: 1627494-13-6

(R)-8-(1-((3,5-Difluorophenyl)Amino)Ethyl)-N,N-Dimethyl-2-Morpholino-4-Oxo-4H-Chromene-6-Carboxamide

Purity: 99%

Molecular weight: 457.47g/mol

Ref: 54-PC108902

AZD8186

CAS: 1627494-13-6

AZD8186

Purity: ≥98%

Molecular weight: 457.47g/mol

Ref: 54-BUP09998

AZD8186

CAS: 1627494-13-6

AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).

Formula: C₂₄H₂₅F₂N₃O₄

Purity: 99.89% - 99.91%

Color and Shape: Solid

Molecular weight: 457.47

Ref: TM-T6773

AZD 8186

Controlled Product

CAS: 1627494-13-6

Applications AZD 8186 is a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers.
References Barlaam, B., et al.: J. Med. Chem., 58, 943 (2015)

Formula: C₂₄H₂₅F₂N₃O₄

Color and Shape: Neat

Molecular weight: 457.48

Ref: TR-A808185

AZD 8186

CAS: 1627494-13-6

AZD 8186 is a potent anti-cancer drug that has shown potent antitumor activity against solid tumors. It has been shown to inhibit the growth of cancer cells by targeting and inhibiting the lipid kinase activity of the tumor cells. AZD 8186 also inhibits the pro-apoptotic protein and induces apoptosis in mouse tumor cells, which may be due to inhibition of polymerase chain reaction (PCR) for DNA replication. This drug also targets cancer tissues in vivo and selectively kills myeloid-derived suppressor cells (MDSCs), which are immunosuppressive cells that promote tumor progression.

Formula: C₂₄H₂₅F₂N₃O₄

Purity: Min. 95%

Molecular weight: 457.47 g/mol

Ref: 3D-FD103345