CAS 162760-96-5

Way 100635

Description:

Way 100635, with the CAS number 162760-96-5, is a selective antagonist of the serotonin receptor subtype 5-HT1A. This compound is primarily used in research settings to investigate the role of 5-HT1A receptors in various physiological and pathological processes, including anxiety, depression, and neurodegenerative diseases. Way 100635 exhibits high affinity for the 5-HT1A receptor, making it a valuable tool for studying serotonin signaling pathways. Its pharmacological profile allows researchers to explore the effects of serotonin modulation on behavior and neurochemistry. Additionally, Way 100635 is often utilized in animal models to assess the therapeutic potential of targeting 5-HT1A receptors in mental health disorders. As with many research chemicals, the safety and handling of Way 100635 require adherence to appropriate laboratory protocols, and its use is typically restricted to controlled environments. Overall, Way 100635 serves as an important compound in the field of neuropharmacology, contributing to our understanding of serotonin's role in the brain.

Formula: C₂₅H₃₄N₄O₂

InChI: InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3

InChI key: InChIKey=SBPRIAGPYFYCRT-UHFFFAOYSA-N

SMILES: O(C)C1=C(C=CC=C1)N2CCN(CCN(C(=O)C3CCCCC3)C4=CC=CC=N4)CC2

Synonyms:

• N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxaMide
• CYCLOHEXANECARBOXAMIDE, N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-, HYDROCHLORIDE (1:3)
• WAY 100635;WAY100635
• Cyclohexanecarboxamide,N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-
• WAY100635 TRIHYDROCHLORIDE
• WAY-100635;WAY 100635; WAY100635
• CYCLOHEXANECARBOXYLIC ACID (2-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-ETHYL)-PYRIDIN-2-YL-AMIDE TRIHYDROCHLORIDE

Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-

CAS: 162760-96-5

Formula: C₂₅H₃₄N₄O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 422.5631

Ref: IN-DA001TEY

N-(2-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Ethyl)-N-(Pyridin-2-Yl)Cyclohexanecarboxamide

CAS: 162760-96-5

N-(2-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Ethyl)-N-(Pyridin-2-Yl)Cyclohexanecarboxamide

Purity: 98%

Molecular weight: 422.56g/mol

Ref: 54-OR1023193

WAY-100635

CAS: 162760-96-5

WAY-100635 is a potent 5-HT 1A receptor antagonist pyramidal neuron firing frequency during conditioned reflexes; a dopamine D4 receptor agonist .

Formula: C₂₅H₃₄N₄O₂

Purity: 98.972%

Color and Shape: Solid

Molecular weight: 422.56

Ref: TM-T21561

WAY 100635

CAS: 162760-96-5

WAY 100635 is a selective 5-HT2 receptor antagonist with high affinity for the α-subunit of the 5-HT2 receptors. WAY 100635 blocks the activation of these receptors by serotonin and other agonists and has been shown to have no effect on dopamine release or binding at dopaminergic sites. This agent has been shown to have a significant effect on locomotor activity in rats, as well as on concentrations of serotonin in the hippocampus. WAY 100635 is also used as a model system for studying the effects of drugs that interact with 5-HT2 receptors. In this system, WAY 100635 binds selectively to 5-HT2A receptors and prevents their activation by serotonin, which results in an increase in extracellular levels of dopamine in the nucleus accumbens.

Formula: C₂₅H₃₄N₄O₂

Purity: Min. 95%

Molecular weight: 422.56 g/mol

Ref: 3D-MGA76096

WAY 100635

Controlled Product

CAS: 162760-96-5

Applications WAY 100635 exhibits high affinity and efficacy at the dopamine D4 receptor (1,2,3). WAY 100635 is a potent 5-HT1A antagonist.

Formula: C₂₅H₃₄N₄O₂

Color and Shape: Neat

Molecular weight: 422.56

Ref: TR-W498665