The chemical substance known as (3S)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one, with the CAS number 1627696-52-9, is characterized by its complex molecular structure, which includes multiple heterocyclic rings. This compound features a pyrimidine ring substituted with a fluorine atom, contributing to its potential biological activity. The isoindolone core provides a framework that is often associated with various pharmacological properties. The presence of a pyrazole moiety further enhances its chemical diversity, potentially influencing its interactions with biological targets. This substance may exhibit specific stereochemistry, as indicated by the (3S) configuration, which can significantly affect its biological activity and binding affinity. Overall, this compound is of interest in medicinal chemistry, particularly in the development of novel therapeutic agents, due to its unique structural features and potential for bioactivity. Further studies would be necessary to elucidate its specific properties, mechanisms of action, and potential applications in drug development.

(3S)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one

1627696-52-9: The chemical substance known as (3S)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one, with the CAS number 1627696-52-9, is characterized by its complex molecular structure, which includes multiple heterocyclic rings. This compound features a pyrimidine ring substituted with a fluorine atom, contributing to its potential biological activity. The isoindolone core provides a framework that is often associated with various pharmacological properties. The presence of a pyrazole moiety further enhances its chemical diversity, potentially influencing its interactions with biological targets. This substance may exhibit specific stereochemistry, as indicated by the (3S) configuration, which can significantly affect its biological activity and binding affinity. Overall, this compound is of interest in medicinal chemistry, particularly in the development of novel therapeutic agents, due to its unique structural features and potential for bioactivity. Further studies would be necessary to elucidate its specific properties, mechanisms of action, and potential applications in drug development.

<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>

CAS 1627696-52-9

(3S)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one

LY3143921

Ref: TM-T60747