CAS 1628343-77-0

ARN 726 (ARN726)

Description:

ARN-726, with the CAS number 1628343-77-0, is a chemical compound that belongs to a class of substances known for their potential therapeutic applications, particularly in the field of oncology. It is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. ARN-726 is often studied for its mechanism of action, which may involve modulation of specific cellular pathways or interactions with particular proteins. The compound's solubility, stability, and pharmacokinetic properties are crucial for its efficacy and safety in potential clinical applications. Additionally, ARN-726 may undergo various forms of testing to evaluate its toxicity, efficacy, and overall pharmacological profile. As research progresses, the understanding of its characteristics and potential uses continues to evolve, highlighting the importance of ongoing studies in drug development and therapeutic innovation.

Formula: C₁₄H₂₄N₂O₃

Synonyms:

• ARN726 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]-carbamate
• ARN 726
• (ARN726)
• Carbamic acid, N-[(3S)-2-oxo-3-azetidinyl]-, 4-cyclohexylbutyl ester

4-Cyclohexylbutyl (S)-(2-oxoazetidin-3-yl)carbamate

CAS: 1628343-77-0

4-Cyclohexylbutyl (S)-(2-oxoazetidin-3-yl)carbamate

Purity: 95%

Molecular weight: 268.36g/mol

Ref: 54-OR1070295

ARN 726

CAS: 1628343-77-0

ARN 726 is a compound that binds to the endocannabinoid system and inhibits the enzyme fatty acid amide hydrolase (FAAH) which breaks down anandamide. This inhibition of FAAH leads to higher levels of anandamide in the brain, which produces antinociceptive effects. ARN 726 has been shown to be effective at reducing inflammatory symptoms in mice by modulating cytokine production. The expression of ARN 726 is localized in tissues that are affected by inflammation, such as the skin and stomach lining. The physicochemical properties of ARN 726 have been characterized by gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR). These studies revealed that ARN 726 is a carbamic acid derivative with a carbamate moiety and a probe for lipid targets that are expressed in the brain.

Formula: C₁₄H₂₄N₂O₃

Purity: Min. 95%

Molecular weight: 268.35 g/mol

Ref: 3D-DQC34377

ARN726

CAS: 1628343-77-0

ARN726, potent NAAA inhibitor, IC50 of 0.073 μM, reduces alcohol craving dose-dependently.

Formula: C₁₄H₂₄N₂O₃

Color and Shape: Solid

Molecular weight: 268.35

Ref: TM-T60456