CAS 1628416-28-3

2-(7-Ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[d]oxazol-6-yl)acetamide

CAS: 1628416-28-3

Formula: C₂₇H₂₃FN₄O₄

Purity: 99%

Molecular weight: 486.4943

Ref: IN-DA01KJZU

CFTR corrector 2

CAS: 1628416-28-3

CFTR corrector 2

Purity: ≥98%

Molecular weight: 486.49g/mol

Ref: 54-BUP10005

CFTR corrector 2

CAS: 1628416-28-3

CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.

Formula: C₂₇H₂₃FN₄O₄

Purity: 99.66%

Color and Shape: Solid

Molecular weight: 486.49

Ref: TM-T5312

CFTR corrector 2

CAS: 1628416-28-3

CFTR corrector 2 is a heterocycle that binds to the CFTR protein. It is an analog of colistimethate sodium, which is a polypeptide antibiotic. The compound has been shown to be effective in treating acute pancreatitis, as well as chronic pancreatitis, by modulating the function of CFTR in the pancreas. CFTR corrector 2 is also a bifunctional compound that encompasses both carboxylate and amide functional groups. This allows it to be conjugated with organic acids such as lactate, glycolate, or acetate and thereby enter cells through passive diffusion. The compound can also be metabolized by cellular enzymes such as esterases or glucuronidases, which hydrolyze these conjugates into monocarboxylates and monamides respectively.

Formula: C₂₇H₂₃FN₄O₄

Purity: Min. 95%

Molecular weight: 486.49 g/mol

Ref: 3D-DQC41628