CAS 162849-95-8

(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane

Description:

The chemical substance with the name "(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane" and CAS number "162849-95-8" is a complex organic compound characterized by its multiple functional groups and stereochemistry. It features a hexane backbone with specific stereocenters at the 2, 3, and 5 positions, indicating its chiral nature. The presence of a tert-butoxycarbonyl (Boc) group suggests it is likely used in peptide synthesis or as a protecting group for amino acids. Additionally, the thiazole moiety indicates potential biological activity, possibly enhancing its interaction with biological targets. The diphenyl and hydroxy groups contribute to its hydrophobic characteristics, which may influence its solubility and reactivity. Overall, this compound's structural complexity and functional diversity suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals or biologically active compounds. Its specific properties, such as melting point, solubility, and reactivity, would require experimental determination for practical applications.

Formula: C₂₈H₃₅N₃O₅S

Synonyms:

• thiazol-5-ylmethyl (2S,3S,5S)-5-tert-butoxycarbonylamino-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate
• Rt-8

N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester

CAS: 162849-95-8

Formula: C₂₈H₃₅N₃O₅S

Color and Shape: Solid

Molecular weight: 525.6596

Ref: IN-DA001TH5

Ritonavir EP Impurity J

CAS: 162849-95-8

Formula: C₂₈H₃₅N₃O₅S

Molecular weight: 525.66

Ref: 4Z-R-2737

Ritonavir EP Impurity J

CAS: 162849-95-8

Formula: C₂₈H₃₅N₃O₅S

Molecular weight: 525.66

Ref: ST-EA-CP-R16010

N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester

Controlled Product

CAS: 162849-95-8

Impurity Ritonavir EP Impurity J
Applications N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester (Ritonavir EP Impurity J) is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor used for the treatment of HIV infections and AIDS.
References Hamada, Y., et al.: Bioorg. Med. Chem., 10, 4155 (2002);

Formula: C₂₈H₃₅N₃O₅S

Color and Shape: White To Off-White

Molecular weight: 525.66

Ref: TR-D472785