CAS 16285-74-8

thieno[3,2-d]pyrimidin-4-amine

Description:

Thieno[3,2-d]pyrimidin-4-amine is a heterocyclic organic compound characterized by a fused ring system that includes both a thiophene and a pyrimidine moiety. This compound features an amine functional group at the 4-position of the pyrimidine ring, which contributes to its reactivity and potential biological activity. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amine group. Thieno[3,2-d]pyrimidin-4-amine is of interest in medicinal chemistry, particularly for its potential as a scaffold in drug development, as it may interact with various biological targets. The compound's structure allows for diverse substitution patterns, which can influence its pharmacological properties. Additionally, it may exhibit properties such as fluorescence or photostability, depending on its specific substituents. Overall, thieno[3,2-d]pyrimidin-4-amine is a versatile compound with applications in research and development within the fields of pharmaceuticals and agrochemicals.

Formula: C₆H₅N₃S

InChI: InChI=1/C6H5N3S/c7-6-5-4(1-2-10-5)8-3-9-6/h1-3H,(H2,7,8,9)

SMILES: c1csc2c1nc[nH]c2=N

thieno[3,2-d]pyrimidin-4-amine

CAS: 16285-74-8

Formula: C₆H₅N₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 151.1890

Ref: IN-DA001THC

Thieno[3,2-d]pyrimidin-4-amine

CAS: 16285-74-8

Thieno[3,2-d]pyrimidin-4-amine

Purity: 97%

Molecular weight: 151.19g/mol

Ref: 54-OR94418

Thieno[3,2-d]pyrimidin-4-amine

CAS: 16285-74-8

Formula: C₆H₅N₃S

Purity: 97%

Molecular weight: 151.19

Ref: 10-F233876

4-Aminothieno[3,2-d]pyrimidine

Controlled Product

CAS: 16285-74-8

Applications 4-Aminothieno[3,2-d]pyrimidine is a useful research intermediate
References Robba, M., et al.: Tetrahedron, 27, 487 (1971); Park, J. H., et al.: Heterocycles, 91, 835 (2015)

Formula: C₆H₅N₃S

Color and Shape: Neat

Molecular weight: 151.19

Ref: TR-A630678

Thieno[3,2-d]pyrimidin-4-amine

CAS: 16285-74-8

Thieno[3,2-d]pyrimidin-4-amine is an inhibitor of the enzyme dihydrofolate reductase. This drug is being studied for the treatment of tuberculosis and other bacterial infections. It is a potent inhibitor of the uptake of thiocyanate by erythrocytes. The metabolic pathway for this drug has been shown to involve oxidation by cytochrome p450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Thieno[3,2-d]pyrimidin-4-amine inhibits the synthesis of purine nucleotides in the mitochondria by inhibiting oxidative phosphorylation at complex III and IV. It also inhibits protein synthesis in bacteria. Thieno[3,2-d]pyrimidin-4-amine has been shown to have antiplasmodial activity against Plasmodium falciparum (

Formula: C₆H₅N₃S

Purity: Min. 95%

Molecular weight: 151.19 g/mol

Ref: 3D-RAA28574