CAS 162870-29-3

(S)-3,5-DIHYDROXYPHENYLGLYCINE

Description:

(S)-3,5-Dihydroxyphenylglycine, with the CAS number 162870-29-3, is an amino acid derivative characterized by the presence of two hydroxyl groups on the phenyl ring, specifically at the 3 and 5 positions. This compound is a chiral molecule, with the (S) configuration indicating the specific spatial arrangement of its atoms. It is known for its role as a selective agonist for certain glutamate receptors, particularly the metabotropic glutamate receptor subtype 2 (mGluR2), which has implications in neuropharmacology and potential therapeutic applications for neurological disorders. The presence of hydroxyl groups contributes to its solubility in polar solvents and may influence its biological activity and interactions with other molecules. Additionally, its structural features allow for hydrogen bonding, which can affect its stability and reactivity in various chemical environments. Overall, (S)-3,5-Dihydroxyphenylglycine is of interest in both research and pharmaceutical contexts due to its unique properties and biological significance.

Formula: C₈H₉NO₄

InChI: InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)/t7-/m0/s1

InChI key: InChIKey=HOOWCUZPEFNHDT-ZETCQYMHSA-N

SMILES: [C@H](C(O)=O)(N)C1=CC(O)=CC(O)=C1

Synonyms:

• (S)-3,5-Dhpg
• (S)-3,5-Dihydroxyphenylglycine hydrate
• (αS)-α-Amino-3,5-dihydroxybenzeneacetic acid
• <span class="text-smallcaps">L</span>-3,5-Dihydroxyphenylglycine
• <span class="text-smallcaps">L</span>-Di-meta-hydroxyphenylglycine
• Benzeneacetic acid, α-amino-3,5-dihydroxy-, (S)-
• Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)-
• S-Dhpg
• L-Di-meta-hydroxyphenylglycine
• (S)-3,5-Dihydroxyphenylglycine
• (S)-3,5-Dihydroxylphenylglycine

Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)-

CAS: 162870-29-3

Formula: C₈H₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 183.1614

Ref: IN-DA001TIP

(S)-2-Amino-2-(3,5-dihydroxyphenyl)acetic acid

CAS: 162870-29-3

(S)-2-Amino-2-(3,5-dihydroxyphenyl)acetic acid

Purity: 98%

Molecular weight: 183.16g/mol

Ref: 54-OR1073903

(S)-3,5-Dihydroxyphenylglycine hydrate

CAS: 162870-29-3

Formula: C₈H₉NO₄·xH₂O

Molecular weight: 183.16 (anhydrous)

Ref: 7W-GK0472

(S)-3,5-Dihydroxylphenylglycine

CAS: 162870-29-3

Applications (S)-3,5-Dihydroxylphenylglycine is a potent agonist of group I metabotropic glutamate receptors mGluR1 and mGluR5. (S)-3,5-Dihydroxylphenylglycine have been utilized for the treatment of neuronal injury and cognitive enhancement.
References Huang, C.C., et al.: Neuropharmacol., 63, 1298 (2012); Ji, M., et al.: J. Neurosci., 32, 12744 (2012);

Formula: C₈H₉NO₄

Color and Shape: Neat

Molecular weight: 183.1614

Ref: TR-D454520

(S)-3,5 DHPG

CAS: 162870-29-3

M03841 - (S)-3,5 DHPG

Formula: C₈H₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 183.163

Ref: 10-M03841

(S)-3,5-Dihydroxylphenylglycine-d4

Controlled Product

CAS: 162870-29-3

Formula: C₈D₄H₅NO₄

Color and Shape: Neat

Molecular weight: 187.186

Ref: TR-D454522

(S)-3,5-DHPG

CAS: 162870-29-3

group I mGlu receptor agonist

Formula: C₈H₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 183.16

Ref: TM-T23289