CAS 1628752-83-9

Palbociclib-d8

CAS: 1628752-83-9

Formula: C₂₄H₂₁D₈N₇O₂

Color and Shape: Yellow Solid

Molecular weight: 455.59

Ref: 4Z-P-196005

Palbociclib-d8

CAS: 1628752-83-9

Palbociclib-d8 (PD 0332991 D8) is the deuterated form of Palbociclib. Palbociclib is a CDK inhibitor that inhibits CDK4 and CDK6.

Formula: C₂₄H₂₁D₈N₇O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 455.58

Ref: TM-T12355

Palbociclib-d8

Controlled Product

CAS: 1628752-83-9

Formula: C₂₄D₈H₂₁N₇O₂

Color and Shape: Neat

Molecular weight: 455.582

Ref: TR-P139902

Palbociclib-d8

Controlled Product

CAS: 1628752-83-9

Palbociclib-d8 is a potential antineoplastic agent that inhibits the aromatase enzyme. It has been shown to inhibit the growth of breast cancer cells by blocking the synthesis of estrogen, which is required for tumor cell proliferation. Palbociclib-d8 binds to the aromatase enzyme and prevents the conversion of androgens into estrogens. This drug has also been shown to reduce tumor metastases in mice by inhibiting DNA replication and protein synthesis, leading to apoptosis. Palbociclib-d8 can be taken orally and has a favorable safety profile in animals; however, it is not yet approved for use in humans.

Formula: C₂₄H₂₁D₈N₇O₂

Purity: Min. 95%

Molecular weight: 455.58 g/mol

Ref: 3D-DQC75283