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CAS 16289-13-7

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Chlorthalidone Impurity G

Description:
Chlorthalidone Impurity G, with the CAS number 16289-13-7, is a chemical compound that is recognized as an impurity associated with the thiazide diuretic chlorthalidone. This substance is typically characterized by its structural similarity to chlorthalidone, which is a sulfonamide derivative. Impurity G may exhibit properties such as solubility in organic solvents and varying stability under different pH conditions. Its presence in pharmaceutical formulations is of concern due to potential impacts on the efficacy and safety of the final product. Analytical methods, such as high-performance liquid chromatography (HPLC), are commonly employed to detect and quantify this impurity in drug formulations. Regulatory guidelines often dictate acceptable limits for impurities to ensure product quality. Understanding the characteristics of Chlorthalidone Impurity G is essential for pharmaceutical development and quality control, as it helps in assessing the purity of chlorthalidone and ensuring compliance with safety standards.
Formula:C14H9Cl2NO2
InChI:InChI=1/C14H9Cl2NO2/c15-11-6-5-8(7-12(11)16)14(19)10-4-2-1-3-9(10)13(18)17-14/h1-7,19H,(H,17,18)
SMILES:c1ccc2c(c1)C(=NC2(c1ccc(c(c1)Cl)Cl)O)O
Synonyms:
  • 3-(3,4-Dichlorophenyl)-3-hydroxy-phthalimidin
  • (3-(3,4-Dichlorophenyl)-3-hydroxy-phthalimidine)
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