CAS 1629063-81-5

GNE-131

CAS: 1629063-81-5

GNE-131

Purity: ≥98%

Molecular weight: 442.57g/mol

Ref: 54-BUP09113

GNE-131

CAS: 1629063-81-5

GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).

Formula: C₂₃H₃₀N₄O₃S

Purity: 98.54% - 99.59%

Color and Shape: Solid

Molecular weight: 442.57

Ref: TM-TQ0014

GNE 131

CAS: 1629063-81-5

A triazole sulphonamide that selectively inhibits sodium channel NaV1.7, by binding to the VSD4 site. GNE 131 demonstrated high potency and metabolic stability in vitro. NaV1.7 is a potential target for the treatment of pain, due to its role in nociception. It has high efficacy in transgenic mouse model of induced pain.

Formula: C₂₃H₃₀N₄O₃S

Purity: Min. 95%

Molecular weight: 442.58 g/mol

Ref: 3D-BG167285