CAS 1629229-37-3

[(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone

Description:

The chemical substance with the name "[(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone" and CAS number "1629229-37-3" is a complex organic compound characterized by its multi-ring structure, which includes a triazole and pyrazine moiety. This compound features a thiadiazole substituent, contributing to its potential biological activity. The presence of a fluorophenyl group suggests that it may exhibit unique electronic properties, potentially influencing its reactivity and interaction with biological targets. The stereochemistry indicated by the (8R) configuration implies specific spatial arrangements that can affect the compound's pharmacological profile. Such compounds are often investigated for their potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various diseases. The intricate structure and functional groups suggest that it may possess interesting properties, including possible antimicrobial or anticancer activities, although specific biological data would be necessary to confirm these effects.

Formula: C₁₆H₁₅FN₆OS

InChI: InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1

InChI key: InChIKey=PPSNFPASKFYPMN-SECBINFHSA-N

SMILES: C[C@@H]1C=2N(C(=NN2)C=3SN=C(C)N3)CCN1C(=O)C4=CC=C(F)C=C4

Synonyms:

• (R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
• [(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone
• (4-Fluorophenyl)[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methanone
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• Fezolinetant
• ESN 364
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• FEZOLINETANT; ESN-364; ESN 364; ESN364

Fezolinetant

CAS: 1629229-37-3

Fezolinetant (ESN-364) is a neurokinin-3 receptor antagonist that is being investigated for menopausal hot flashes.Cost-effective and quality-assured.

Formula: C₁₆H₁₅FN₆OS

Purity: 98.62% - 99.7%

Color and Shape: Solid

Molecular weight: 358.39

Ref: TM-T15278

Fezolinetant

CAS: 1629229-37-3

Formula: C₁₆H₁₅FN₆OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.3933

Ref: IN-DA01EOC7

Fezolinetant

CAS: 1629229-37-3

Fezolinetant

Purity: ≥98%

Molecular weight: 358.39g/mol

Ref: 54-BUP04385

Fezolinetant

CAS: 1629229-37-3

Formula: C₁₆H₁₅FN₆OS

Molecular weight: 358.40

Ref: 4Z-F-240001

Fezolinetant-d4

CAS: 1629229-37-3

Formula: C₁₆H₁₁D₄FN₆OS

Molecular weight: 362.42

Ref: 4Z-F-240002

Fezolinetant

CAS: 1629229-37-3

Fezolinetant is a drug for the treatment of menopausal symptoms. It is designed to be administered as a single dose, with the primary analysis being a questionnaire on the frequency and severity of symptoms. Fezolinetant has been shown to be efficacious in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Fezolinetant also prevents cancer in mice by inhibiting the invasion and migration of tumor cells. The drug binds to receptors in cells that are involved in cancer cell growth and proliferation, which blocks the production of proteins that are essential for tumor cell division. This drug also has an efficient method of delivery, which may reduce side effects.

Formula: C₁₆H₁₅FN₆OS

Purity: Min. 95%

Molecular weight: 358.39 g/mol

Ref: 3D-EQC22937