CAS 1630-83-7
:4-bromoestra-1,3,5(10)-triene-3,17-diol
Description:
4-Bromoestra-1,3,5(10)-triene-3,17-diol, with the CAS number 1630-83-7, is a synthetic derivative of estradiol, a naturally occurring estrogen. This compound features a bromine atom at the 4-position of the steroid nucleus, which can influence its biological activity and receptor binding affinity. The presence of hydroxyl groups at the 3 and 17 positions contributes to its solubility and reactivity, making it relevant in various biochemical applications. The triene structure indicates the presence of conjugated double bonds, which can enhance its stability and influence its interaction with biological targets. This compound is primarily studied for its potential effects in hormone-related therapies and research into estrogenic activity. Its unique structural modifications may also provide insights into the development of selective estrogen receptor modulators (SERMs) and other therapeutic agents. As with many steroid derivatives, its pharmacological properties, including efficacy and safety, are of significant interest in medicinal chemistry and endocrinology.
Formula:C18H23BrO2
InChI:InChI=1/C18H23BrO2/c1-18-9-8-11-10-4-6-15(20)17(19)13(10)3-2-12(11)14(18)5-7-16(18)21/h4,6,11-12,14,16,20-21H,2-3,5,7-9H2,1H3
SMILES:CC12CCC3c4ccc(c(c4CCC3C1CCC2O)Br)O
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Found 4 products.
4-Bromo 17β-Estradiol
CAS:Controlled Product<p>Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.<br>References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)<br></p>Formula:C18H23BrO2Color and Shape:NeatMolecular weight:351.28
