CAS 1630203-25-6

3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-5-methoxy-N-(3-mor pholinopropyl)benzamide

CAS: 1630203-25-6

3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-5-methoxy-N-(3-morpholinopropyl)benzamide is a potent and selective inhibitor of the receptor for nerve growth factor. It blocks NGF binding to its receptor, preventing NGF from activating the receptor and transmitting signals that stimulate cellular proliferation. 3MPAB has been shown to inhibit the activation of potassium channels by Ligand. It may also have an effect on calcium channels, as well as other ion channels, due to its ability to bind to various sites on protein surfaces.

Formula: C₄₃H₅₁N₇O₈S

Purity: Min. 95%

Molecular weight: 826 g/mol

Ref: 3D-FQC20325

TOP1362

CAS: 1630203-25-6

TOP1362: a kinase inhibitor for dry eye and ocular inflammation; targets p38α, Syk, Src, Lck; reduces cytokines and cell infiltration.

Formula: C₄₃H₅₁N₇O₈S

Color and Shape: Solid

Molecular weight: 825.97

Ref: TM-T70346