CAS 163042-96-4

1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE

Description:

The chemical substance known as 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-beta-D-ribofuranuronamide, with the CAS number 163042-96-4, is a purine derivative characterized by its complex structure, which includes a purine base, a deoxyribose sugar moiety, and various substituents such as a chlorine atom and an iodophenyl group. This compound exhibits properties typical of nucleoside analogs, which can influence biological processes, particularly in the context of antiviral or anticancer activities. The presence of halogen atoms (chlorine and iodine) may enhance its reactivity and biological interactions. Additionally, the methylation of the nitrogen in the ribofuranuronamide structure can affect its solubility and permeability, potentially influencing its pharmacokinetic properties. Overall, this compound's unique structural features suggest it may have significant implications in medicinal chemistry and drug development, particularly in targeting specific biological pathways or mechanisms.

Formula: C₁₈H₁₈ClIN₆O₄

InChI: InChI=1/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1

Synonyms:

• 2-Cl-Ib-Meca
• Cl-IB-MECA, 2-Chloro-N6-(3-iodobenzyl)-adenosine-5μ-N-methyluronamide
• (2S,3S,4R,5R)-5-{2-chloro-6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide (non-preferred name)
• Cf-102
• 1-(2-Chloro-6-(((3-iodophenyl)methyl)amino)-(9H)-purin-9-yl)-1-deoxy-N-methyl-beta-D-ribofuranuronamide

β-D-Ribofuranuronamide, 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-

CAS: 163042-96-4

Formula: C₁₈H₁₈ClIN₆O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 544.7308

Ref: IN-DA001TN0

(2S,3S,4R,5R)-5-[2-Chloro-6-[(3-Iodophenyl)Methylamino]Purin-9-Yl]-3,4-Dihydroxy-N-Methyloxolane-2-Carboxamide

CAS: 163042-96-4

(2S,3S,4R,5R)-5-[2-Chloro-6-[(3-Iodophenyl)Methylamino]Purin-9-Yl]-3,4-Dihydroxy-N-Methyloxolane-2-Carboxamide

Purity: ≥98%(subject to the measured value)

Molecular weight: 544.73g/mol

Ref: 54-OR1024427

Namodenoson

CAS: 163042-96-4

Namodenoson

Purity: ≥98%

Molecular weight: 544.73g/mol

Ref: 54-BUP03257

Chloro-IB-MECA

CAS: 163042-96-4

Formula: C₁₈H₁₈ClIN₆O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 544.73

Ref: 3B-C3601

Namodenoson

CAS: 163042-96-4

Formula: C₁₈H₁₈ClIN₆O₄

Molecular weight: 544.73

Ref: 4Z-N-130001

Namodenoson-13C-d3

CAS: 163042-96-4

Formula: C₁₇₁₃CH₁₅D₃ClIN₆O₄

Molecular weight: 548.75

Ref: 4Z-N-130003

Namodenoson-d6

CAS: 163042-96-4

Formula: C₁₈H₁₂D₆ClIN₆O₄

Molecular weight: 550.77

Ref: 4Z-N-130002

Namodenoson

CAS: 163042-96-4

Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.

Formula: C₁₈H₁₈ClIN₆O₄

Purity: 98.97%

Color and Shape: Solid

Molecular weight: 544.73

Ref: TM-T6884

2-Cl-IB-MECA

CAS: 163042-96-4

Agonist of A3 adenosine receptor; antineoplastic

Formula: C₁₈H₁₈ClIN₆O₄

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 544.73 g/mol

Ref: 3D-NC30706

2-Cl-IB-MECA-13C,d3

Controlled Product

CAS: 163042-96-4

Formula: CC₁₇D₃H₁₅ClIN₆O₄

Color and Shape: Neat

Molecular weight: 548.742

Ref: TR-C576232

2-Cl-IB-MECA

Controlled Product

CAS: 163042-96-4

Applications 2-Cl-IB-MECA acts as an A3 adenosine receptor-selective nucleoside.
References Tosh, D. et al.: J. Med. Chem., 55, 4847 (2012);

Formula: C₁₈H₁₈ClIN₆O₄

Color and Shape: Neat

Molecular weight: 544.73

Ref: TR-C576230