VNPP433-3β, with the CAS number 1630820-51-7, is a synthetic compound that belongs to a class of substances known for their potential therapeutic applications, particularly in the field of neuroscience. This compound is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. VNPP433-3β is primarily studied for its effects on neuroreceptors, and it may exhibit properties that modulate neurotransmitter systems, potentially influencing conditions such as anxiety or depression. The compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for understanding its efficacy and safety profile. Additionally, research into VNPP433-3β may involve evaluating its interactions with other drugs and its overall impact on cellular pathways. As with many experimental compounds, further studies are necessary to fully elucidate its mechanisms of action and therapeutic potential. Always refer to the latest scientific literature for the most current information regarding its characteristics and applications.

VNPP433-3β

1630820-51-7: VNPP433-3β, with the CAS number 1630820-51-7, is a synthetic compound that belongs to a class of substances known for their potential therapeutic applications, particularly in the field of neuroscience. This compound is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. VNPP433-3β is primarily studied for its effects on neuroreceptors, and it may exhibit properties that modulate neurotransmitter systems, potentially influencing conditions such as anxiety or depression. The compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for understanding its efficacy and safety profile. Additionally, research into VNPP433-3β may involve evaluating its interactions with other drugs and its overall impact on cellular pathways. As with many experimental compounds, further studies are necessary to fully elucidate its mechanisms of action and therapeutic potential. Always refer to the latest scientific literature for the most current information regarding its characteristics and applications.

VNPP433-3β acts as a molecular glue degrader, targeting the androgen receptor (AR) and its splice variants (AR-Vs) as well as MAP kinase-interacting serine/threonine protein kinase Mnk1/2. It effectively inhibits the proliferation of cancer cells LNCaP, C4-2B, and CWR22Rv1, with GI50 values of 0.2, 0.3, and 0.31 μM, respectively. Additionally, VNPP433-3β shows favorable pharmacokinetics in CD-1 mice and suppresses tumor growth in the CWR22Rv1 xenograft mouse model.

CAS 1630820-51-7

VNPP433-3β

VNPP433-3β

Ref: TM-T88141