
CAS 163130-29-8
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Found 3 products.
Toremifene N-Oxide Fumarate
CAS:Formula:C26H28ClNO2·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:421.97 116.07Toremifene N-Oxide-d6
CAS:Controlled ProductFormula:C26D6H22ClNO2Color and Shape:NeatMolecular weight:427.996Toremifene-N-oxide
CAS:<p>Toremifene-N-oxide is a drug that has been shown to have genotoxic effects in human liver cells in an incubated system. Toremifene-N-oxide is the active form of toremifene, which is a selective estrogen receptor modulator (SERM). Toremifene-N-oxide is metabolized by peroxidases and can react with reactive oxygen species (ROS) to produce DNA damage. It also binds to DNA at the site of supercoiled DNA, leading to changes in the molecule's structure. Toremifene-N-oxide has been shown to have an optimum pH of 7.4 and ionization mass of 367. This drug binds to lactoperoxidase found in human liver cells and produces reactive molecules that cause oxidative DNA damage.</p>Formula:C26H28ClNO2Purity:Min. 95%Molecular weight:421.96 g/mol


