The chemical substance with the name "(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl((1r,4R)-4-aminocyclohexyl)carbamate" and CAS number "1631953-52-0" is a complex organic compound characterized by its intricate stereochemistry and functional groups. It features a spirocyclic structure, which contributes to its three-dimensional conformation and potential biological activity. The presence of a methoxy group and an oxirane ring indicates reactivity and potential for further chemical transformations. Additionally, the carbamate moiety suggests possible interactions with biological targets, making it of interest in medicinal chemistry. The specific stereochemistry, denoted by the R and S configurations, is crucial for determining the compound's pharmacological properties, as it can influence binding affinity and selectivity for biological receptors. Overall, this compound exemplifies the complexity often found in drug-like molecules, highlighting the importance of stereochemistry in the design of therapeutics.

(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl((1r,4R)-4-aminocyclohexyl)carbamate

1631953-52-0: The chemical substance with the name "(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl((1r,4R)-4-aminocyclohexyl)carbamate" and CAS number "1631953-52-0" is a complex organic compound characterized by its intricate stereochemistry and functional groups. It features a spirocyclic structure, which contributes to its three-dimensional conformation and potential biological activity. The presence of a methoxy group and an oxirane ring indicates reactivity and potential for further chemical transformations. Additionally, the carbamate moiety suggests possible interactions with biological targets, making it of interest in medicinal chemistry. The specific stereochemistry, denoted by the R and S configurations, is crucial for determining the compound's pharmacological properties, as it can influence binding affinity and selectivity for biological receptors. Overall, this compound exemplifies the complexity often found in drug-like molecules, highlighting the importance of stereochemistry in the design of therapeutics.

<p>SDX-7539 is a selective MetAP2 inhibitor that inhibits the proliferation of HUVEC, with an IC50 of 120 μM. It has demonstrated antitumor activity in xenografted NSCLC in athymic nude mice.</p>

CAS 1631953-52-0

(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl((1r,4R)-4-aminocyclohexyl)carbamate

SDX-7539

Ref: TM-T209478