CAS 1632051-40-1

1-[(3α,5β)-3-Hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-1H-pyrazole-4-carbonitrile

Description:

1-[(3α,5β)-3-Hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-1H-pyrazole-4-carbonitrile is a synthetic compound characterized by its complex steroidal structure, which includes a pregnane backbone modified with a hydroxyl group and a carbonitrile moiety. The presence of the pyrazole ring indicates potential biological activity, as pyrazoles are often associated with various pharmacological properties. This compound is likely to exhibit lipophilicity due to its steroidal nature, which may influence its solubility and permeability in biological systems. The hydroxyl group can participate in hydrogen bonding, potentially affecting its interactions with biological targets. Additionally, the carbonitrile group may contribute to its reactivity and ability to form complexes with metal ions or other biomolecules. Overall, this compound's unique structural features suggest it may have applications in medicinal chemistry, particularly in the development of steroid-based therapeutics or as a research tool in studying steroid hormone pathways. However, specific biological activities and safety profiles would require further investigation through empirical studies.

Formula: C₂₅H₃₅N₃O₂

InChI: InChI=1S/C25H35N3O2/c1-24(30)9-7-18-17(11-24)3-4-20-19(18)8-10-25(2)21(20)5-6-22(25)23(29)15-28-14-16(12-26)13-27-28/h13-14,17-22,30H,3-11,15H2,1-2H3/t17-,18+,19-,20-,21+,22-,24-,25+/m1/s1

InChI key: InChIKey=HARRKNSQXBRBGZ-GVKWWOCJSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@@]4([C@](CC3)(C[C@](C)(O)CC4)[H])[H])(CC1)[H])[H])(CC[C@@H]2C(CN5C=C(C#N)C=N5)=O)[H]

Synonyms:

• 1-[(3α,5β)-3-Hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-1H-pyrazole-4-carbonitrile
• Zuranolone
• 1H-Pyrazole-4-carbonitrile, 1-[(3α,5β)-3-hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-
• SAGE 217
• 1-[2-[(3R,5R,8R,9R,10S,13S,14S,17S)-3-hydroxy-3,13-dimethyl-2,4,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl]pyrazole-4-carbonitrile
• 1H-Pyrazole-4-carbonitrile, 1-[(3α,5β)-3-hydroxy-3-methyl-20-oxo-19-norpregnan-21-yl]-
• SGE 797

Zuranolone

CAS: 1632051-40-1

Formula: C₂₅H₃₅N₃O₂

Molecular weight: 409.57

Ref: 4Z-Z-062001

SAGE-217

Controlled Product

CAS: 1632051-40-1

SAGE-217 is a novel antidepressant drug that has been shown to be effective in the treatment of depression. The drug is orally administered and is rapidly absorbed, with peak plasma concentrations occurring within one hour. It binds to GABA receptors and blocks the binding of the neurotransmitter gamma-aminobutyric acid (GABA) to its receptor, which reduces brain activity and has an anti-anxiety effect. SAGE-217 may also have other effects on neurotransmitters, such as serotonin or dopamine, but this remains unclear.

Formula: C₂₅H₃₅N₃O₂

Purity: Min. 95%

Molecular weight: 409.56 g/mol

Ref: 3D-HQC05140

SAGE-217

CAS: 1632051-40-1

SAGE-217

Purity: 98%

Molecular weight: 409.56g/mol

Ref: 54-BISN0069