CAS 163222-33-1: Ezetimibe

Description: Ezetimibe is a pharmaceutical compound primarily used to lower cholesterol levels in patients with hyperlipidemia. It functions by inhibiting the absorption of cholesterol at the intestinal brush border, thereby reducing the amount of cholesterol that enters the bloodstream. Ezetimibe is often prescribed in conjunction with statins to enhance lipid-lowering effects. The substance has a molecular formula of C24H21F2N3O3 and a molecular weight of approximately 409.44 g/mol. It is characterized by its white to off-white crystalline powder form, which is practically insoluble in water but soluble in organic solvents like methanol and ethanol. Ezetimibe is typically administered orally and has a half-life that allows for once-daily dosing. Its safety profile is generally favorable, with common side effects including gastrointestinal disturbances. The compound is marketed under various brand names and is included in treatment regimens for cardiovascular disease prevention. Overall, Ezetimibe represents a significant advancement in cholesterol management, particularly for patients who are statin-intolerant or require additional lipid-lowering therapy.

Formula: C₂₄H₂₁F₂NO₃

InChI: InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

InChI key: InChIKey=OLNTVTPDXPETLC-XPWALMASSA-N

SMILES: O=C1N(C2=CC=C(F)C=C2)C(C3=CC=C(O)C=C3)C1CCC(O)C4=CC=C(F)C=C4

Synonyms:

• (-)-Sch 58235
• (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
• (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235
• (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
• 1-(4-Fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)azetidin-2-one
• 1-(4-Fluorophenyl)-3-[3-(4-Fluorophenyl)-3-Hydroxy-Propyl]-4-(4-Hydroxyphenyl)-Azetidin-2-One
• 1-(4-Flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone
• 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-
• 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, [3R-[3α(S*),4β]]-
• Ezedoc
• Ezentia
• EzetimibeC24H21F2N03
• Ezetimide
• Ezetrol
• Ezitimibe&Int
• Zetia
• Ezitimibe∬ EzetimibeC24H21F2N03
• Ezetimibe

Ezetimibe

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Purity: >95.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

Lactams, nesoi

• Formula: C₂₄H₂₁F₂NO₃
• Color and Shape: White Powder
• Molecular weight: 409.14895

2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 409.4252

Ezetimibe

CAS: 163222-33-1

Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is …

• Formula: C₂₄H₂₁F₂NO₃
• Purity: 97.28% - 99.97%
• Color and Shape: Solid
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

• Purity: ≥98%
• Molecular weight: 409.43g/mol

Ezetimibe

CAS: 163222-33-1

• Purity: 99%
• Molecular weight: 409.43g/mol

Ezetimibe

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Purity: ≥ 98.0%
• Color and Shape: White to almost white powder
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Color and Shape: Neat
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

• Formula: C₂₄H₂₁F₂NO₃
• Color and Shape: White
• Molecular weight: 409.43

Ezetimibe

CAS: 163222-33-1

• Purity: 95%+
• Molecular weight: 409.433013916016

Ezetimibe - Bio-X ™

CAS: 163222-33-1

Ezetimibe is a lipid-lowering compound that inhibits cholesterol absorption. This drug helps to lower cholesterol …

• Formula: C₂₄H₂₁F₂NO₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 409.43 g/mol

Ezetimibe

CAS: 163222-33-1

Inhibitor of cholesterol transporter NPC1L1

• Formula: C₂₄H₂₁F₂NO₃
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 409.43 g/mol

3'-Dehydroxy-1,2-seco Ezetimibe Sodium Salt

CAS: 163222-33-1

• Formula: C₂₄H₂₂F₂NNaO₃
• Color and Shape: Neat
• Molecular weight: 433.423