CAS 163253-35-8

7-[(4S)-4-amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-quinoline-3-carboxylic acid hydrate

Description:

The chemical substance known as "7-[(4S)-4-amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-quinoline-3-carboxylic acid hydrate," with the CAS number 163253-35-8, is a complex organic compound characterized by its unique structural features. It contains a quinoline core, which is a bicyclic structure known for its biological activity, particularly in medicinal chemistry. The presence of multiple functional groups, including an amino group, a carboxylic acid, and halogen substituents (chlorine and fluorine), suggests potential interactions with biological targets, making it of interest in drug development. The spirocyclic structure contributes to its three-dimensional conformation, which can influence its pharmacokinetic properties. Additionally, the hydrate form indicates that the compound can associate with water molecules, which may affect its solubility and stability. Overall, this compound's intricate structure and functionalization position it as a candidate for further investigation in therapeutic applications, particularly in the context of antimicrobial or anticancer research.

Formula: C₁₉H₂₀ClF₂N₃O₄

InChI: InChI=1/C19H18ClF2N3O3.H2O/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19;/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28);1H2/t10-,12?,13+;/m0./s1

Synonyms:

• 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrate (1:1)
• Sitafkoxacin hydrate
• Sitafloxacin Sesquihydrate
• Sitafloxacin hydrate

3-QUINOLINECARBOXYLIC ACID,7-[(7S)-7-AMINO-5-AZASPIRO[2.4]HEPT-5-YL]-8-CHLORO-6-FLUORO-1-[(1R,2S)-2-FLUOROCYCLOPROPYL]-1,4-DIHYDRO-4-OXO-, HYDRATE (2:3)

CAS: 163253-35-8

Formula: C₃₈H₄₂Cl₂F₄N₆O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 873.6745

Ref: IN-DA00ABLR

Sitafloxacin Hydrate

CAS: 163253-35-8

Sitafloxacin Hydrate

Purity: ≥98%

Molecular weight: 436.84g/mol

Ref: 54-BUP12803

Sitafloxacin Hydrate

CAS: 163253-35-8

Sitafloxacin Hydrate

Purity: 98%

Molecular weight: 427.83g/mol

Ref: 54-BISN0320

Sitafloxacin monohydrate

CAS: 163253-35-8

Formula: C₁₉H₂₀ClF₂N₃O₄

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to beige powder

Molecular weight: 427.83

Ref: 7W-GA7129

Sitafloxacin Hydrate

CAS: 163253-35-8

Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.

Formula: C₁₉H₁₈ClF₂N₃O₃H₂O

Purity: 99.73% - 99.77%

Color and Shape: Solid

Molecular weight: 436.84

Ref: TM-T6349

Sitafloxacin Sesquihydrate

Controlled Product

CAS: 163253-35-8

Applications Antibacterial
References Suzuki, T., et al.: Anal. Sci., 16, 343 (2000), Payne G., et al.: Brit. J. Clin. Pharmacol., 59, 244 (2005), Okuda J., et al.: Microbiol. immunol., 51, 467 (2007), Okumura R., et al.: Chemother., 55, 262 (2009),

Formula: C₁₉H₁₈ClF₂N₃O₃·3H₂O

Color and Shape: White To Off-White

Molecular weight: 873.67

Ref: TR-S490920

Sitafloxacin sesquihydrate

CAS: 163253-35-8

Sitafloxacin sesquihydrate is a fourth-generation fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating respiratory, urinary, and gastrointestinal infections.

Formula: C₁₉H₁₈ClF₂N₃O₃•(H₂O)₁

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 436.84 g/mol

Ref: 3D-FS27840