CAS 163380-20-9

Ezetimibe Diacetate

Description:

Ezetimibe Diacetate, with the CAS number 163380-20-9, is a chemical compound primarily known for its role as a cholesterol absorption inhibitor. It is a derivative of Ezetimibe, which is used in the treatment of hyperlipidemia to lower cholesterol levels in the bloodstream. The compound features a specific molecular structure that includes an acetate group, enhancing its pharmacological properties. Ezetimibe Diacetate is typically characterized by its moderate solubility in organic solvents and limited solubility in water, which influences its bioavailability and absorption in the body. The compound acts by selectively inhibiting the intestinal absorption of cholesterol and related phytosterols, leading to a decrease in the amount of cholesterol delivered to the liver. This mechanism results in a compensatory increase in the clearance of cholesterol from the bloodstream. Ezetimibe Diacetate is often studied for its efficacy in combination therapies with statins to provide a more comprehensive approach to managing cholesterol levels and reducing cardiovascular risk.

Formula: C₂₈H₂₅F₂NO₅

Synonyms:

• Ezetimibe Diacetate
• 2-Azetidinone, 3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-[4-(acetyloxy)phenyl]-1-(4-fluorophenyl)-, (3R,4S)-
• [4-[(2S,3R)-3-[(3R)-3-acetyloxy-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenyl] acetate

Ezetimibe Diacetate

Controlled Product

CAS: 163380-20-9

Applications Protected Ezetimibe derivative.
References Rosenblum, S., et al.: J. Med. Chem., 41, 973 (1998),

Formula: C₂₈H₂₅F₂NO₅

Color and Shape: Neat

Molecular weight: 493.5

Ref: TR-E975020

Ezetimibe Diacetate

CAS: 163380-20-9

Formula: C₂₈H₂₅F₂NO₅

Molecular weight: 493.5

Ref: ST-EA-CP-E6060