CAS 163521-12-8: Vilazodone

Description: Vilazodone is a pharmaceutical compound primarily used as an antidepressant, classified as a selective serotonin reuptake inhibitor (SSRI) and a partial agonist at the serotonin receptor 5-HT1A. Its chemical formula is C26H28N4O2S, and it features a complex structure that includes a benzodioxole moiety and a thiophene ring. Vilazodone is known for its dual mechanism of action, which not only increases serotonin levels in the brain by inhibiting its reuptake but also enhances serotonergic neurotransmission through its partial agonist activity. This unique profile may contribute to its efficacy in treating major depressive disorder while potentially offering a favorable side effect profile compared to traditional SSRIs. The substance is typically administered orally and is metabolized primarily in the liver, with a half-life that supports once-daily dosing. Common side effects may include gastrointestinal disturbances, insomnia, and sexual dysfunction, similar to other antidepressants. Overall, vilazodone represents a significant advancement in the pharmacological management of depression.

Formula: C₂₆H₂₇N₅O₂

InChI: InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)

InChI key: InChIKey=SGEGOXDYSFKCPT-UHFFFAOYSA-N

SMILES: N#CC=1C=CC=2NC=C(C2C1)CCCCN3CCN(C=4C=CC=5OC(=CC5C4)C(=O)N)CC3

Synonyms:

• 1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine
• 2-Benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-
• 5-(4-(4-(5-Cyanoindol-3-yl)butyl)-1-piperazinyl)-2-benzofurancarboxamide
• 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide
• Emd 515259
• Unii-S239O2Oov3
• Vilazodone

2-Benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-

CAS: 163521-12-8

• Formula: C₂₆H₂₇N₅O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 441.5249

Vilazodone

CAS: 163521-12-8

Vilazodone (SB659746A): an SSRI and 5-HT-1A agonist, boosts serotonin to treat depression and anxiety.

• Formula: C₂₆H₂₇N₅O₂
• Purity: 99.61%
• Color and Shape: Light Yellow Solid
• Molecular weight: 441.52

Vilazodone hydrochloride

CAS: 163521-12-8

• Formula: C₂₆H₂₇N₅O₂·HCl
• Purity: ≥ 99.0%
• Color and Shape: White powder
• Molecular weight: 477.98

Vilazodone

CAS: 163521-12-8

Stability Very Hygroscopic Applications It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A …

• Formula: C₂₆H₂₇N₅O₂
• Color and Shape: Neat
• Molecular weight: 441.52

N-(5-Cyano-1H-indol-3-yl)butyl Vilazodone Piperazinium Salt

CAS: 163521-12-8

• Formula: C₃₉H₄₀NN₆O₂•X
• Color and Shape: Neat
• Molecular weight: 638.78+(XX.XX)

Vilazodone Carboxylic Acid-d4

CAS: 163521-12-8

• Formula: C₂₆H₂₇N₅O₂
• Color and Shape: Neat
• Molecular weight: 441.52

5-[4-[4-(5-Cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide

CAS: 163521-12-8

Vilazodone is a selective serotonin reuptake inhibitor (SSRI) that was designed to have low affinity …

• Formula: C₂₆H₂₇N₅O₂
• Purity: Min. 95%
• Molecular weight: 441.53 g/mol