CAS 163521-20-8

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

Description:

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate is a chemical compound characterized by its unique structure, which includes a benzofuran moiety and a piperazine ring. This compound typically appears as a white to off-white solid and is soluble in organic solvents, reflecting its moderate polarity. The presence of the ethyl ester group contributes to its reactivity, making it a potential candidate for various chemical reactions, including esterification and nucleophilic substitutions. The piperazine ring is known for its biological activity, often serving as a pharmacophore in drug design, which may suggest potential therapeutic applications. Additionally, the compound may exhibit interesting pharmacological properties, although specific biological activity would depend on further studies. Safety data and handling precautions should be considered, as with any chemical substance, to ensure proper laboratory practices. Overall, Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate represents a compound of interest in medicinal chemistry and organic synthesis.

Formula: C₁₅H₁₈N₂O₃

Synonyms:

• 2-Benzofurancarboxylic acid,5-(1-piperazinyl)-,ethyl
• esterVilazodone
• Ethyl 5-(piperazin-1-yl)-1-benzofuran-2-carboxylate
• Vilazodone Key interMediates
• 2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-,ethyl ester
• Ethyl 5-piperazin-1-ylbenzofuran-2-carboxylate
• 5-(1-piperazinyl)-2-Benzofurancarboxylic acid ethyl ester
• 1-(2-Ethoxycarbonylbenzofuran-5-yl)piperazine
• Vlazodone
• Vilazodone interMediate
• Ethyl 5-(1-Piperazinyl)benzofuran-2-carboxylate
• Ethyl 5-(1-Piperazinyl)benzofuran-2-2-carboxylate
• ethyl 5-(piperazine-1-yl)benzofuran-2-carboxylate
• Eehyl 5-(piperazin-1-yl)benzofuran-2-carboxylate
• 5-(1-piperazinyl)benzofuran-2-carboxylic acid ethyl ester

2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-, ethyl ester

CAS: 163521-20-8

Formula: C₁₅H₁₈N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 274.3150

Ref: IN-DA001U6X

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

CAS: 163521-20-8

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

Purity: 98%

Molecular weight: 274.32g/mol

Ref: 54-OR90893

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

CAS: 163521-20-8

Purity: 95.0%

Molecular weight: 274.32000732421875

Ref: 10-F228876

5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester

Controlled Product

CAS: 163521-20-8

Applications 5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester is used in the synthesis of benzofuran derivatives for mycobacterium tuberculosis DNA GyrB inhibition.
References Reddy, K.I., et. al.: Bioorg. Med. Chem., 22, 6552 (2014)

Formula: C₁₅H₁₈N₂O₃

Color and Shape: Neat

Molecular weight: 274.32

Ref: TR-P480635

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

CAS: 163521-20-8

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate is a potent inhibitor of the bacterial enzyme DNA gyrase. It has been shown to inhibit the growth of Mycobacterium tuberculosis in cell cultures. Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate binds to the active site of bacterial DNA gyrase and inhibits its activity, thereby inhibiting bacterial DNA replication and transcription. The inhibition of this enzyme leads to decreased levels of ATP production and subsequent inhibition of protein synthesis. This compound also interacts with ATPases, which are enzymes that produce ATP in eukaryotic cells, leading to the disruption of energy production.

Formula: C₁₅H₁₈N₂O₃

Purity: Min. 95%

Molecular weight: 274.32 g/mol

Ref: 3D-NGA52120