CAS 163655-37-6

MAZ51

Description:

MAZ51, with the CAS number 163655-37-6, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and pharmacology. It is characterized by its specific molecular structure, which contributes to its biological activity. MAZ51 is known to act as a selective inhibitor, targeting specific pathways or receptors, which makes it a subject of interest in drug development. The compound typically exhibits properties such as solubility in organic solvents, stability under standard laboratory conditions, and a defined melting point, although these specific physical properties can vary based on the formulation and purity. Its mechanism of action often involves modulation of cellular processes, which can lead to therapeutic effects in certain diseases. As with many chemical substances, safety and handling precautions are essential, as MAZ51 may have associated toxicity or require specific storage conditions to maintain its integrity. Overall, MAZ51 represents a significant compound in the ongoing exploration of new therapeutic agents.

Formula: C₂₁H₁₈N₂O

InChI: InChI=1/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)/b18-13+

Synonyms:

• 3-(4-Dimethylamino-Naphthalen-1-Ylmethylene)-1,3-Dihydro-Indol-2-One

2H-Indol-2-one, 3-[[4-(dimethylamino)-1-naphthalenyl]methylene]-1,3-dihydro-

CAS: 163655-37-6

Formula: C₂₁H₁₈N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 314.3804

Ref: IN-DA001UAG

MAZ51

CAS: 163655-37-6

MAZ51

Purity: ≥98%

Molecular weight: 314.38g/mol

Ref: 54-BUP02102

MAZ51

CAS: 163655-37-6

MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.

Formula: C₂₁H₁₈N₂O

Purity: 98.53%

Color and Shape: Solid

Molecular weight: 314.38

Ref: TM-T8496

MAZ51

Controlled Product

CAS: 163655-37-6

Applications MAZ51 is an indolinone compound that selectively antagonizes the activation of VEGFR-3 by VEGF-C without blocking VEGF-C mediated stumulation of VEGFR-2. This reduces proliferation and induces apoptosis in various cancer cells and suppresses tumor growth.
References Kirkin, V. et al.: Eur. J. Biochem., 268, 5530 (2001);

Formula: C₂₁H₁₈N₂O

Color and Shape: Neat

Molecular weight: 379.408

Ref: TR-M198100