
CAS 163712-68-3
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Found 3 products.
2Z-Nalfurafine
CAS:Controlled Product<p>Applications 2Z-Nalfurafine is a geometric isomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.<br>References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)<br></p>Formula:C28H32N2O5Color and Shape:NeatMolecular weight:476.562Z-Nalfurafine-d3
CAS:Controlled ProductFormula:C28H29D3N2O5Color and Shape:NeatMolecular weight:479.582Z-Nalfurafine (1 mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C28H32N2O5Color and Shape:Single SolutionMolecular weight:476.56
