CAS 16373-93-6

2'-Deoxyadenosine hydrate

Description:

2'-Deoxyadenosine hydrate is a nucleoside that plays a crucial role in the structure of DNA. It consists of the purine base adenine attached to a deoxyribose sugar, specifically at the 2' position, which lacks a hydroxyl group, distinguishing it from ribonucleosides. The hydrate form indicates the presence of water molecules associated with the compound, which can influence its solubility and stability. This substance is typically a white to off-white crystalline powder and is soluble in water, making it suitable for various biochemical applications. In biological systems, 2'-deoxyadenosine is involved in the synthesis of DNA and is a building block for nucleotides. Its derivatives are also significant in pharmacology, particularly in the development of antiviral and anticancer agents. The compound's molecular structure allows for hydrogen bonding and stacking interactions, which are essential for the stability of nucleic acid structures. Overall, 2'-deoxyadenosine hydrate is a vital component in molecular biology and biochemistry, with implications in both research and therapeutic contexts.

Formula: C₁₀H₁₅N₅O₄

InChI: InChI=1/C10H13N5O3.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7;/h3-7,16-17H,1-2H2,(H2,11,12,13);1H2/t5-,6+,7+;/m0./s1

Synonyms:

• 2-Deoxyadenosine monohydrate
• 2-deoxyadenosine 2-Deoxyadenosine
• 2'-Deoxyadenosine Hydrate (1:1)

2'-Deoxyadenosine Monohydrate

CAS: 16373-93-6, 958-09-8

Formula: C₁₀H₁₃N₅O₃·H₂O

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 269.27

Ref: 3B-D0046

2′-Deoxyadenosine Monohydrate

CAS: 16373-93-6

Formula: C₁₀H₁₅N₅O₄

Purity: 98%

Molecular weight: 269.261

Ref: 10-F547301

2'-Deoxyadenosine monohydrate, 99%

CAS: 16373-93-6

2?-Deoxyadenosineise is used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2?-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes. This Thermo Scientific Chemicals brand product was originally part o

Formula: C₁₀H₁₃N₅O₃

Purity: 99%

Color and Shape: White, Powder

Molecular weight: 251.25

Ref: 02-A11166

Adenosine, 2'-​deoxy-​, hydrate (1:1)

CAS: 16373-93-6

Formula: C₁₀H₁₅N₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 269.2572

Ref: IN-DA001UCU

2'-Deoxyadenosine monohydrate

CAS: 16373-93-6

Deoxyadenosine is a deoxyribonucleoside and adenosine derivative with a hydrogen replacing a hydroxyl group at ribose's 2' position.

Formula: C₁₀H₁₅N₅O₄

Purity: 99.9% - 99.93%

Color and Shape: Powder

Molecular weight: 269.26

Ref: TM-T2752

2'-Deoxyadenosine monohydrate

CAS: 16373-93-6

2'-Deoxyadenosine monohydrate

Purity: ≥98%

Molecular weight: 269.26g/mol

Ref: 54-BUP17654

2'-Deoxyadenosine monohydrate, 10mM (in DMSO)

CAS: 16373-93-6

2'-Deoxyadenosine monohydrate, 10mM (in DMSO)

Purity: ≥98%

Molecular weight: 269.26g/mol

Ref: 54-BUP19977

2'-Deoxyadenosine monohydrate

CAS: 16373-93-6

2'-Deoxyadenosine monohydrate

Purity: 98%

Color and Shape: White Solid

Molecular weight: 269.26g/mol

Ref: 54-BID2034

2''-Deoxyadenosine monohydrate

CAS: 16373-93-6

Formula: C₁₀H₁₃N₅O₃·H₂O

Purity: (HPLC) ≥ 99.0%

Color and Shape: White to off-white powder

Molecular weight: 269.26

Ref: 7W-GN7468

2'-Deoxyadenosine monohydrate

CAS: 16373-93-6

Formula: C₁₀H₁₃N₅O₃

Purity: 95%~99%

Molecular weight: 251.246

Ref: BP-BP4231

2'-Deoxyadenosine Monohydrate

Controlled Product

CAS: 16373-93-6

Applications 2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),

Formula: C₁₀H₁₃N₅O₃·H₂O

Color and Shape: Neat

Molecular weight: 269.26

Ref: TR-D231620

2'-Deoxyadenosine monohydrate

CAS: 16373-93-6

2'-Deoxyadenosine monohydrate (2'-dA) is an adenosine nucleotide that is synthesized by the enzyme adenosine kinase. It is a competitive inhibitor of phosphodiesterase and inhibits the activity of this enzyme, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis. 2'-dA has been shown to have sublethal effects on neurons at concentrations that are below those required for neuronal death and apoptosis. This may be due to its ability to inhibit the synthesis of ATP, thereby limiting the production of phosphoryl groups from ATP. The inhibition of ATP synthesis also reduces the amount of energy available for other processes within cells.

Formula: C₁₀H₁₃N₅O₃•H₂O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 269.26 g/mol

Ref: 3D-ND04011

2'-Deoxyadenosine-13C2,15N

Controlled Product

CAS: 16373-93-6, 958-09-8

Formula: C₂C₈H₁₂₁₅NN₄O₃

Color and Shape: Neat

Molecular weight: 253.213

Ref: TR-D232171

2-Deoxy-β-D-adenosine Monohydrate

CAS: 16373-93-6

Formula: C₁₀H₁₅N₅O₄

Molecular weight: 269.26

Ref: ST-EA-CP-A88104

2-Deoxyadenosine Monohydrate extrapure, 98%

CAS: 16373-93-6

Formula: C₁₀H₁₃N₅O₃·H₂O

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 269.26

Ref: SR-83158