CAS 163759-50-0

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-

Description:

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl- is a modified nucleoside that exhibits unique structural characteristics due to the presence of various substituents on its ribose sugar and base components. This compound features a uridine backbone, which is a nucleoside composed of a ribose sugar and the nitrogenous base uracil. The modifications include a 5'-O-bis(4-methoxyphenyl)phenylmethyl group and a 2'-O-(2-methoxyethyl) group, which enhance its solubility and potentially its biological activity. The presence of methoxy groups contributes to its lipophilicity, which may influence its interaction with biological membranes and receptors. Additionally, the methyl group at the 5-position of the uracil base can affect its hydrogen bonding and stability. Such modifications are often explored for their potential therapeutic applications, including antiviral and anticancer properties, as they can alter the pharmacokinetics and bioavailability of the nucleoside. Overall, this compound represents a class of synthetic nucleoside analogs with promising biochemical properties.

Formula: C₃₄H₃₈N₂O₉

Synonyms:

• 5'-O-Dmtr- 2'-O-(2-Methoxyethyl)-5-Methyl-Uridine
• 5'-O-(Bis(4-Methoxyphenyl)Phenylmethyl)-2'-O-(2-Methoxyethyl)-5-Methyluridine

5'-O-DMTr- 2'-O-(2-Methoxyethyl)-5-methyl- uridine

CAS: 163759-50-0

Formula: C₃₄H₃₈N₂O₉

Purity: %

Color and Shape: Solid

Molecular weight: 618.6735

Ref: IN-DA00ANQ4

DMT-2'-O-MOE-Tr

CAS: 163759-50-0

DMT-2'-O-MOE-Tr

Purity: 95+%

Molecular weight: 618.67g/mol

Ref: 54-OR1075607

5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine

CAS: 163759-50-0

5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH open;

Formula: C₃₄H₃₈N₂O₉

Color and Shape: Solid

Molecular weight: 618.67

Ref: TM-TNU1094

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

CAS: 163759-50-0

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.

Formula: C₃₄H₃₈N₂O₉

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 618.67 g/mol

Ref: 3D-ND36302

1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 163759-50-0

Purity: 95+%

Molecular weight: 618.6829834

Ref: 10-F605781