CAS 1638250-96-0

Formula: C19H17N7O3

InChI: InChI=1S/C19H17N7O3/c1-24-17-16(18(28)25(2)19(24)29)26(11-20-17)10-15(27)21-14-9-8-13(22-23-14)12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3,(H,21,23,27)

InChI key: QTRXIFVSTWXRJJ-UHFFFAOYSA-N

SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NC3=NN=C(C=C3)C4=CC=CC=C4

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

CAS: 1638250-96-0

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-N-(6-Phenylpyridazin-3-Yl)Acetamide

Formula: C₁₉H₁₇N₇O₃

Purity: 98%

Molecular weight: 391.38

Ref: 54-OR1023188

ETC-159

CAS: 1638250-96-0

ETC-159

Formula: C₁₉H₁₇N₇O₃

Purity: ≥95%

Molecular weight: 391.38

Ref: 54-BUP06111

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Formula: C₁₉H₁₇N₇O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 391.3834

Ref: IN-DA001UF2

ETC-159

CAS: 1638250-96-0

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(6-phenylpyridazin-3-yl)acetamide

Formula: C₁₉H₁₇N₇O₃

Purity: 98%

Molecular weight: 391.38

Ref: IN-DG630410

ETC-159

CAS: 1638250-96-0

ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.

Formula: C₁₉H₁₇N₇O₃

Purity: 96.87% - 99.30%

Color and Shape: Solid

Molecular weight: 391.38

Ref: TM-T4043

7H-PURINE-7-ACETAMIDE, 1,2,3,6-TETRAHYDRO-1,3-DIMETHYL-2,6-DIOXO-N-(6-PHENYL-3-PYRIDAZINYL)-

CAS: 1638250-96-0

Purity: 98%

Molecular weight: 391.3909912

Ref: 10-F801801

1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide

Controlled Product

CAS: 1638250-96-0

Applications 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide is a novel potent PORCN inhibitor that blocks the secretion and activity of all Wnts.
References Madan, B., et al.: Oncogene, 35, 2197-2207 (2016);

Formula: C₁₉H₁₇N₇O₃

Color and Shape: Neat

Molecular weight: 391.383

Ref: TR-T293433

ETC-159

Controlled Product

CAS: 1638250-96-0

ETC-159 is a monoclonal antibody that binds to and inhibits the function of β-catenin. It is an orally administered drug that has been shown to be effective for the treatment of solid tumours, such as colorectal cancer. ETC-159 blocks the cell signaling pathways mediated by β-catenin, which may lead to tumor suppression. This drug also has the ability to inhibit TNF-α and suppressor genes in cancer cells, which are involved in tumor growth. The chemical structure of this molecule includes a pan-PI3K inhibitor with a potential application in inhibiting cancers that are not responsive to conventional therapy.

Formula: C₁₉H₁₇N₇O₃

Purity: Min. 95%

Molecular weight: 391.38 g/mol

Ref: 3D-NQC25096