CAS 1638644-62-8

6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride

Description:

6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride is a complex organic compound characterized by its unique bicyclic structure, which incorporates multiple heteroatoms, including nitrogen and oxygen. This compound features a chloro substituent, contributing to its reactivity and potential biological activity. The presence of the dioxadiazacyclohexadecine framework suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. The hydrochloride salt form indicates enhanced solubility in aqueous environments, which is advantageous for biological assays and drug formulation. Its intricate structure may also confer specific pharmacokinetic properties, influencing absorption, distribution, metabolism, and excretion (ADME) profiles. As with many synthetic compounds, the safety and efficacy of this substance would require thorough investigation through preclinical and clinical studies to ascertain its potential therapeutic applications and any associated toxicity.

Formula: C₁₆H₁₅ClN₄O₂

Synonyms:

• RIPK2 inhibitor OD36
• OD 36 hydrochloride
• OD-36,OD36
• 13H-1,16-Etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine, 6-chloro-10,11,14,17-tetrahydro-
• OD-36
• 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride

OD36

CAS: 1638644-62-8

OD36

Purity: ≥98%

Molecular weight: 330.77g/mol

Ref: 54-BUP02342

OD 36

Controlled Product

CAS: 1638644-62-8

Formula: C₁₆H₁₅ClN₄O₂

Color and Shape: Neat

Molecular weight: 330.769

Ref: TR-O241600

OD 36

CAS: 1638644-62-8

OD 36 is an anti-VEGF compound that is used as a diagnostic tool to detect the presence of VEGF in the eye. It is also used for intravitreal injection to treat retinal disorders such as age-related macular degeneration and diabetic retinopathy. OD 36 has been shown to be resistant to surfactants, making it suitable for use in aqueous solutions. This chemical does not have any intrinsic anti-oxidant properties, but can be stabilized by the addition of other anti-oxidants. OD 36 is insoluble in water and should be stored at low temperatures to prevent precipitation. OD 36 has shown no immunogenicity or toxicity in animals, although it may cause pigmentosa when injected into the eye.

Formula: C₁₆H₁₅ClN₄O₂

Purity: Min. 95%

Molecular weight: 330.77 g/mol

Ref: 3D-NQC64462

OD36

CAS: 1638644-62-8

OD36: Potent RIPK2 inhibitor, IC50=5.3 nM; hinders ALK2 signaling and osteogenesis, KD=37 nM; targets ALK2 ATP pocket.

Formula: C₁₆H₁₅ClN₄O₂

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 330.77

Ref: TM-T35694