CAS 163973-98-6

FSH RECEPTOR-BINDING INHIBITOR FRAGMENT (BI-10)

Description:

FSH Receptor-Binding Inhibitor Fragment (BI-10) is a synthetic peptide that acts as an antagonist to the follicle-stimulating hormone (FSH) receptor. This compound is characterized by its ability to inhibit the binding of FSH to its receptor, thereby modulating reproductive hormone signaling pathways. The molecular structure of BI-10 includes specific amino acid sequences that confer its binding properties and biological activity. It is primarily utilized in research settings to study reproductive biology and the mechanisms of hormone action. The inhibition of FSH receptor activity can have implications in various therapeutic areas, including fertility treatments and hormone-related disorders. As a small molecule, BI-10 is typically evaluated for its pharmacological properties, including potency, selectivity, and potential side effects. Its CAS number, 163973-98-6, serves as a unique identifier for regulatory and research purposes, facilitating the tracking of its use in scientific literature and clinical studies.

Formula: C₄₂H₆₇N₁₃O₁₉

Synonyms:

• (4S)-4-[[2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-5-[(2-amino-2-oxoethyl)amino]-5-oxopentanoic acid
• FSH RECEPTOR-BINDING INHIBITOR FRAGMENT (BI-10)
• Glycinamide, L-threonyl-L-α-glutamyl-L-asparaginyl-L-leucyl-L-α-glutamyl-L-prolyl-L-asparaginylglycyl-L-α-glutamyl- (9CI)
• H-THR-GLU-ASN-LEU-GLU-PRO-ASN-GLY-GLU-GLY-NH2

Fsh receptor-binding inhibitor fragment(bi-10)

CAS: 163973-98-6

FSH antagonist bi-10 suppresses ovulation, induces follicular atresia, and may help in ovarian cancer by downregulating FSHR/ERβ.

Formula: C₄₂H₆₇N₁₃O₁₉

Color and Shape: Solid

Molecular weight: 1058.06

Ref: TM-T76566