CAS 164104-49-8

2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3S,11bS)-

Description:

2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3S,11bS)-, identified by its CAS number 164104-49-8, is a complex organic compound characterized by its unique bicyclic structure that incorporates a quinolizine moiety. This compound features multiple functional groups, including hydroxyl (-OH) and methoxy (-OCH3) groups, which contribute to its chemical reactivity and potential biological activity. The stereochemistry indicated by the (2S,3S,11bS) configuration suggests specific spatial arrangements of its atoms, which can influence its interactions in biological systems. The presence of a branched alkyl chain (2-methylpropyl) enhances its hydrophobic characteristics, potentially affecting its solubility and permeability in biological membranes. Such compounds may exhibit various pharmacological properties, making them of interest in medicinal chemistry and drug development. Overall, the structural complexity and functional diversity of this compound suggest potential applications in various fields, including pharmaceuticals and organic synthesis.

Formula: C₁₉H₂₉NO₃

Synonyms:

• (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol
• TETRABENAZINE METABOLITE C
• (2S,3S,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol
• (2S,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
• 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3S,11bS)-

(2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol

CAS: 164104-49-8

Formula: C₁₉H₂₉NO₃

Color and Shape: Solid

Molecular weight: 319.4385

Ref: IN-DA001UNB

Tetrabenazine Impurity 39 (2S, 3S, 11bS)

CAS: 164104-49-8

Formula: C₁₉H₂₉NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 319.45

Ref: 4Z-T-7815

(2S,3S,11bS)-Dihydrotetrabenazine

Controlled Product

CAS: 164104-49-8

Applications (2S,3S,11bS)-Dihydrotetrabenazine is a vesicular monoamine transporter 2 (VMAT2) inhibitor. It also has various medical uses including treatment for asthma, anxiety and dementia.
References Yao, Z., et al.: Eur. J. Med. Chem. 46, 1841 (2011); Duffield, A. J. and Williams, N. A. PCT Int. Appl. WO 2010026434 A1 20100311(2010); Grayson, B. et al.: PCT Int. Appl. WO 2009150474 A1 20091217 (2009); Nichols, P. P. Brit. UK Pat. Appl. GB 2463451 A 20100317 (2010)

Formula: C₁₉H₂₉NO₃

Color and Shape: Neat

Molecular weight: 319.438

Ref: TR-D454905

trans (2,3)-Dihydro Tetrabenazine-d6

Controlled Product

CAS: 164104-49-8

Formula: C₁₉D₆H₂₃NO₃

Color and Shape: Neat

Molecular weight: 325.475

Ref: TR-D449657

Tetrabenazine Related Impurity 5

CAS: 164104-49-8

Formula: C₁₉H₂₉NO₃

Molecular weight: 319.45

Ref: ST-EA-CP-T104029