CAS 1642-54-2

Diethylcarbamazine citrate

Description:

Diethylcarbamazine citrate is a synthetic organic compound primarily used as an anthelmintic agent, particularly in the treatment of filariasis and other parasitic infections. It is characterized by its chemical structure, which includes a carbamate functional group and ethyl substituents, contributing to its pharmacological properties. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Diethylcarbamazine citrate works by immobilizing and killing the parasites, facilitating their elimination from the host's body. Its mechanism of action involves interference with the metabolism of the parasites, leading to their eventual death. The compound is generally well-tolerated, although it may cause side effects such as dizziness, headache, or gastrointestinal disturbances in some patients. Due to its specific therapeutic applications, it is important to use diethylcarbamazine citrate under medical supervision, ensuring proper dosage and monitoring for any adverse reactions.

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

InChI: InChI=1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=PGNKBEARDDELNB-UHFFFAOYSA-N

SMILES: C(N(CC)CC)(=O)N1CCN(C)CC1.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Synonyms:

• 1-Diethylcarbamoyl-4-methylpiperazine dihydrogen citrate
• 1-Methyl-4-diethylcarbamoylpiperazine citrate
• 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, citrate (1:1)
• Banocide
• Caricide
• Caritrol
• Decc
• Dicarocide
• Diethyl Carbazine Citrate
• Diethyl carbamazine citrate
• DiethylCarbazine Citrate
• Diethylcarbamazine Acid Citrate
• Diethylcarbamazine Dihydrogen Citrate
• Dirocide
• Ditrazin citrate
• Ditrazine
• Ethodryl citrate
• Ethylaminoazine citrate
• Filaribits
• Filazine
• Franocide
• Franozan
• Hetrazan
• Longicid
• Loxuran
• N,N-Diethyl-4-methyl-1-piperazinecarboxamide dihydrogen citrate
• N,N-diethyl-4-methylpiperazine-1-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate (1:1)

Diethylcarbamazine Citrate

CAS: 1642-54-2, 90-89-1

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 391.42

Ref: 3B-D1898

Diethylcarbamazine Citrate

CAS: 1642-54-2

Color and Shape: Neat

Ref: 61-FOR1640.00

Diethylcarbamazine citrate

CAS: 1642-54-2

Diethylcarbamazine citrate

Formula: C₁₀H₂₁N₃OC₆H₈O₇

Purity: 99.9%

Color and Shape: Off-White

Molecular weight: 391.19546

Ref: 47-737

DIETHYLCARBAMAZINE DIHYDROGEN CITRATE RS

CAS: 1642-54-2

DIETHYLCARBAMAZINE DIHYDROGEN CITRATE RS

Formula: C₁₆H₂₉N₃O₈

Color and Shape: Powder

Molecular weight: 391.4168

Ref: 41-ICRS0287

DIETHYLCARBAMAZINE CITRATE CRS

CAS: 1642-54-2

DIETHYLCARBAMAZINE CITRATE CRS

Formula: C₁₆H₂₉N₃O₈

Color and Shape: Powder

Molecular weight: 391.4168

Ref: 41-D1300000

Diethylcarbamazine Citrate

CAS: 1642-54-2

Drugs containing a pyrimidine ring (whether or not hydr

Formula: C₁₆H₂₉N₃O₈

Color and Shape: Powder

Molecular weight: 391.4 g/mol

Ref: 45-1193006

Diethylcarbamazine (citrate)

CAS: 1642-54-2

Formula: C₁₆H₂₉N₃O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 391.4168

Ref: IN-DA003PHU

Diethylcarbamazine citrate

CAS: 1642-54-2

Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Purity: 99.61%

Color and Shape: White Crystalline Powder And Animals (Epa 1998)

Molecular weight: 391.42

Ref: TM-T1420

Diethylcarbamazine citrate

CAS: 1642-54-2

Diethylcarbamazine citrate

Purity: ≥98%

Molecular weight: 391.42g/mol

Ref: 54-BUP16913

Diethylcarbamazine citrate salt

CAS: 1642-54-2

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Molecular weight: 391.42

Ref: 7W-GA5083

Diethylcarbamazine citrate

Controlled Product

CAS: 1642-54-2

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 391.42

Ref: 04-C12605700

Diethylcarbamazine Citrate

Controlled Product

CAS: 1642-54-2

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 391.42

Ref: 86-MM1640.00

N,N-Diethyl-4-methylpiperazine-1-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate

CAS: 1642-54-2

Purity: 95.0%

Molecular weight: 391.4209899902344

Ref: 10-F437465

Diethylcarbamazine Citrate

Controlled Product

CAS: 1642-54-2

Formula: C₁₀H₂₁N₃O·C₆H₈O₇

Color and Shape: Off-White

Molecular weight: 391.42

Ref: TR-D443900

Diethylcarbamazine citrate

CAS: 1642-54-2

Diethylcarbamazine citrate is an anthelmintic drug that is used to treat helminth infections. It inhibits the growth of nematodes by binding to the polymerase chain and inhibiting protein synthesis. Diethylcarbamazine citrate has been shown to be effective in treating bowel disease, which may be due to its ability to inhibit inhibitor molecules. This drug also has low potency for a number of bacterial species, such as Escherichia coli, Klebsiella pneumoniae, and Bacillus cereus, making it a good choice for use in vitro assays. Diethylcarbamazine citrate has a pyrazole ring in its structure that can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase or conjugated with glucuronic acid.

Formula: C₁₆H₂₉N₃O₈

Purity: Min. 95%

Molecular weight: 391.42 g/mol

Ref: 3D-FD21831