CAS 1643326-82-2

Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-

Description:

The chemical substance known as Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-, with the CAS number 1643326-82-2, is a complex organic compound characterized by its unique structural features. It contains a urea functional group, which is known for its role in various biological processes and applications in pharmaceuticals. The compound exhibits a bicyclic structure that includes a cyclopropabenzofuran moiety and a naphthyridine derivative, contributing to its potential biological activity. The presence of trifluorophenyl groups suggests enhanced lipophilicity and may influence its interaction with biological targets. This compound may be of interest in medicinal chemistry, particularly for its potential therapeutic applications. Its specific properties, such as solubility, stability, and reactivity, would depend on the overall molecular structure and substituents, making it a candidate for further investigation in drug development and related fields.

Formula: C₂₄H₁₇F₃N₄O₄

Synonyms:

• Brimarafenib
• 1-[(1S,1aS,6bS)-5-[(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl)oxy]-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-1-yl]-3-(2,4,5-trifluorophenyl)urea
• Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-
• BGB-3245(Brimarafenib)

Brimarafenib

CAS: 1643326-82-2

Brimarafenib

Purity: ≥98%

Molecular weight: 482.41g/mol

Ref: 54-BUP21182

Brimarafenib

CAS: 1643326-82-2

Brimarafenib is a selective RAF dimerization inhibitor, which can inhibit BRAF and CRAF, and exhibits inhibitory effects on a variety of RAF mutations.

Formula: C₂₄H₁₇F₃N₄O₄

Purity: 98.32%

Color and Shape: Solid

Molecular weight: 482.41

Ref: TM-T89116