CAS 164579-32-2: Pantoprazole sodium sesquihydrate
Description:Pantoprazole sodium sesquihydrate is a proton pump inhibitor primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH-dependent solubility profile, which enhances its absorption in the gastrointestinal tract. The chemical formula reflects its sodium salt form, indicating the presence of sodium ions, and the sesquihydrate designation indicates that it contains one and a half molecules of water for each molecule of pantoprazole. Pantoprazole acts by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a decrease in gastric acid secretion. Its pharmacokinetics show a rapid onset of action, with peak plasma concentrations typically occurring within a few hours after administration. The substance is generally well-tolerated, though it may have side effects such as headache, gastrointestinal disturbances, and, in rare cases, more serious effects like kidney issues or vitamin B12 deficiency with long-term use.
Formula:C16H15F2N3O4SH2O·Na
InChI:InChI=1S/C16H15F2N3O4S.Na.H2O/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;;/h3-7,15H,8H2,1-2H3,(H,20,21);;1H2
InChI key:InChIKey=RJRBTVMZZGMTQI-UHFFFAOYSA-N
SMILES:[Na].O=S(C1=NC=2C=C(OC(F)F)C=CC2N1)CC3=NC=CC(OC)=C3OC.O
- Synonyms:
- 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, sodium salt, hydrate (2:3)
- 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt, hydrate (2:2:3)
- 1H-benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
- 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole, sodium salt, sesquihydrate
- Allpan
- Pantocip
- Pantodac
- Pantop
- Pantoprazole sodium hydrate
- Pantoprazole sodium sesquihydrate
- See more synonyms
- Pantosec
- Unii-6871619Q5X
![1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium sal…](https://static.cymitquimica.com/products/IN/thumb/DA001UYC.jpg)
