CAS 16462-27-4

2,4-DIAMINOPYRIMIDINE-5-CARBONITRILE

Description:

2,4-Diaminopyrimidine-5-carbonitrile is an organic compound characterized by its pyrimidine ring structure, which features two amino groups at the 2 and 4 positions and a cyano group at the 5 position. This compound is typically a solid at room temperature and is known for its potential applications in pharmaceuticals and agrochemicals, particularly as a building block in the synthesis of various biologically active molecules. The presence of amino groups contributes to its basicity and reactivity, allowing it to participate in various chemical reactions, such as nucleophilic substitutions and condensation reactions. The cyano group enhances its electronic properties, making it useful in the development of dyes and other functional materials. Additionally, 2,4-diaminopyrimidine-5-carbonitrile may exhibit biological activity, which warrants further investigation for its potential therapeutic uses. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₅H₅N₅

InChI: InChI=1/C5H5N5/c6-1-3-2-9-5(8)10-4(3)7/h2H,(H4,7,8,9,10)

InChI key: InChIKey=OYUQCQCQLDTRHQ-UHFFFAOYSA-N

SMILES: C(#N)C=1C(N)=NC(N)=NC1

Synonyms:

• 2,4-Diamino-5-Cyano-Pyrimidine
• 2,4-Diamino-5-Pyrimidinecarbonitrile
• 2,4-Diamino-5-cyanopyrimidine
• 2,4-Diaminopyrimidine-5-carbonitrile ,97%
• 5-Pyrimidinecarbonitrile, 2,4-diamino-
• 5-Pyrimidinecarbonitrile, 2,4-diamino- (6CI,8CI,9CI)
• NSC 135235
• 2,4-Diaminopyrimidine-5-carbonitrile
• 2,4-DIAMINOPYRIMIDINE-5-CARBONITRILE ISO 9001：2015 REACH
• 2,4-Diaminopyrimidine-5-carbonitriL

5-Pyrimidinecarbonitrile, 2,4-diamino-

CAS: 16462-27-4

Formula: C₅H₅N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 135.1267

Ref: IN-DA001V02

2,4-Diaminopyrimidine-5-carbonitrile

CAS: 16462-27-4

2,4-Diaminopyrimidine-5-carbonitrile

Purity: 96%

Molecular weight: 135.13g/mol

Ref: 54-OR480761

2,4-Diaminopyrimidine-5-carbonitrile

Controlled Product

CAS: 16462-27-4

Applications 2,4-Diaminopyrimidine-5-carbonitrile is used as an intermediate for the preparation of medicines and agrochemicals (1).
References (1) Otzen, T., et al.: J. Med. Chem., 47, 240 (2004)

Formula: C₅H₅N₅

Color and Shape: Neat

Molecular weight: 135.13

Ref: TR-D416740

2,4-Diaminopyrimidine-5-carbonitrile

CAS: 16462-27-4

2,4-Diaminopyrimidine-5-carbonitrile (2,4-DAP) is a potent inhibitor of the bacterial enzymes d-alanine:glyoxylate aminotransferase (dAGAT) and d-alanine:pyruvate aminotransferase (dAPAT). These enzymes are involved in amino acid metabolism and are potential targets for anticancer therapy. 2,4-DAP has inhibitory properties against cancer cells and has been shown to lead to apoptosis in cervical cancer cells. It also inhibits the synthesis of cellulases by binding to the catalytic site of these enzymes. 2,4-DAP is an inhibitor that binds to the enzyme model protein DnaA at a site that is different from its native substrate ATP. This binding prevents ATP from binding to the protein, inhibiting DNA replication and transcription.

Formula: C₅H₅N₅

Purity: Min. 95%

Molecular weight: 135.13 g/mol

Ref: 3D-FD21495

2,4-Diaminopyrimidine-5-carbonitrile

CAS: 16462-27-4

Formula: C₅H₅N₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 135.13

Ref: 10-F078789