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CAS 1648909-73-2

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Found 2 products.
  • Bis-imidazole phenol idh1 inhibitor
    Biosynth
    + Info

    Bis-imidazole phenol idh1 inhibitor

    CAS:
    <p>Bis-imidazole phenol IDH1 inhibitor is a small-molecule therapeutic, which is a novel compound synthesized to specifically target mutant forms of isocitrate dehydrogenase 1 (IDH1). It operates by binding to the mutant IDH1 enzyme and inhibiting its aberrant function, which involves converting alpha-ketoglutarate to an oncometabolite, 2-hydroxyglutarate (2-HG). This conversion leads to epigenetic changes that drive the tumorigenesis process.</p>
    Formula:C22H30N4O
    Purity:Min. 95%
    Molecular weight:366.5 g/mol

    Ref: 3D-YQC90973

    25mg
    826.00€
    50mg
    1,246.00€
    100mg
    1,732.00€
  • Mutant IDH1-IN-3
    Targetmol
    + Info

    Mutant IDH1-IN-3

    CAS:
    Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor targeting the mutant isocitrate dehydrogenase 1 (IDH1), with an IC50 of 13 nM for R132HIDH1. It effectively suppresses the production of D-2-hydroxyglutarate (2HG) in cells and is applicable for research in oncology.
    Formula:C22H30N4O
    Color and Shape:Solid
    Molecular weight:366.5

    Ref: TM-T204372